Reactome | HSP90:STIP1:HSP70:nascent protein [cytosol]

HSP90:STIP1:HSP70:nascent protein [cytosol]

Stable Identifier

R-HSA-3371444

Type

Complex

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
21700222	Client-loading conformation of the Hsp90 molecular chaperone revealed in the cryo-EM structure of the human Hsp90:Hop complex Southworth, DR, Agard, DA	Mol. Cell	2011

Participants

components

Participates

as an output of

STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Homo sapiens)

as an input of

ATP binding to HSP90 triggers conformation change (Homo sapiens)

Inferred To

HSP90:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Caenorhabditis elegans)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Danio rerio)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Dictyostelium discoideum)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Schizosaccharomyces pombe)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)

HSP90:STIP1:HSP70:nascent protein [cytosol] (Xenopus tropicalis)

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