Reactome | RPS19BP1 [nucleoplasm]

RPS19BP1 [nucleoplasm]

Stable Identifier

R-HSA-3371427

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

AROS, Active regulator of SIRT1, 40S ribosomal protein S19-binding protein 1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q86WX3 RPS19BP1

Gene Names

RPS19BP1, AROS

Chain

chain:1-136

Reference Genes

BioGPS Gene:91582 RPS19BP1

COSMIC (genes):RPS19BP1 RPS19BP1

CTD Gene:91582 RPS19BP1

dbSNP Gene:91582 RPS19BP1

ENSEMBL:ENSG00000187051 RPS19BP1

HGNC:28749 RPS19BP1

KEGG:hsa:91582 RPS19BP1

Monarch:91582 RPS19BP1

NCBI Gene:91582 RPS19BP1

OMIM:610225 RPS19BP1

UCSC:Q86WX3 RPS19BP1

Reference Transcript

RefSeq:NM_194326.3 RPS19BP1

Other Identifiers

11716827_at

16935264

225148_PM_at

225148_at

3961252

3961254

3961255

3961256

3961257

3961258

3961259

3961260

3961261

3961262

3961263

3961264

3961265

3961266

3961267

65601_at

80726_s_at

80728_i_at

8076225

88032_at

91582

A_24_P740705

GE87498

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005829

GO:0019899

GO:0032040

GO:0042274

GO:0043226

HMNXSV003035428

Hs.81915.1.A1_3p_at

ILMN_2177965

PH_hs_0035814

TC22000807.hg

This entity regulates

Positively

SIRT1 binds to HSF1 (Homo sapiens)

Inferred To

Rps19bp1 [nucleoplasm] (Mus musculus)

Rps19bp1 [nucleoplasm] (Rattus norvegicus)

RPS19BP1 [nucleoplasm] (Bos taurus)

RPS19BP1 [nucleoplasm] (Gallus gallus)

RPS19BP1 [nucleoplasm] (Sus scrofa)

Cross References

ENSEMBL

ENSG00000187051, ENST00000334678, ENSP00000333948

OpenTargets

ENSG00000187051

GeneCards

RPS19BP1

HPA

ENSG00000187051-RPS19BP1

PRO

Q86WX3

Pharos - Targets

Q86WX3

GlyGen

Q86WX3

PDB

8BBK, 7MQA

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96EB6 SIRT1	1	SIRT1 [nucleoplasm] (R-HSA-427531)	0.733	11
UniProt:Q5JR59-3 MTUS2			0.556	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:Q8IUG1 KRTAP1-3	1	KRTAP1-3 [cytosol] (R-HSA-6809866)	0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:O00399 DCTN6	1	DCTN6 [cytosol] (R-HSA-2029035)	0.527	2
UniProt:Q8WVZ9 KBTBD7	1	KBTBD7 [cytosol] (R-HSA-5658415)	0.527	3
UniProt:Q9NZ32 ACTR10	4	ACTR10 [cytosol] (R-HSA-6801556) ACTR10 [azurophil granule lumen] (R-HSA-6801080) ACTR10 [extracellular region] (R-HSA-6806245) ACTR10 [ficolin-1-rich granule lumen] (R-HSA-6801072)	0.527	2
UniProt:Q86V97 KBTBD6	1	KBTBD6 [cytosol] (R-HSA-8863221)	0.527	3

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