GPX7 [endoplasmic reticulum lumen]

Stable Identifier
R-HSA-3341316
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Glutathione peroxidase 7, GPX7_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
21215271 Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation

Saaranen, MJ, Salo, KE, Raykhel, IB, Nguyen, VD, Karala, AR, Alanen, HI, Lappi, AK, Wang, L, Wang, CC, Ruddock, LW

J. Mol. Biol. 2011
23123197 Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease

Lo, WT, Hsieh, YH, Shew, JY, Wei, PC, Jiang, X, Chen, PL, Wang, JM, Jeng, YM, Hsu, PH, Lee, KF, Tsai, MD, Su, MI, Lee, WH, Chang, YC, Weng, JY

Mol. Cell 2012
External Reference Information
External Reference
UniProt:Q96SL4 GPX7
Gene Names
GPX7, GPX6, UNQ469/PRO828
Chain
signal peptide:1-19, chain:20-187
Reference Genes
BioGPS Gene:2882 GPX7
COSMIC (genes):GPX7 GPX7
CTD Gene:2882 GPX7
dbSNP Gene:2882 GPX7
ENSEMBL:ENSG00000116157.6 GPX7
HGNC:4559 GPX7
KEGG Gene (Homo sapiens):2882 GPX7
Monarch:2882 GPX7
NCBI Gene:2882 GPX7
OMIM:615784 GPX7
UCSC:Q96SL4 GPX7
Reference Transcript
Other Identifiers
11723293_at
16664748
213170_PM_at
213170_at
2336440
2336441
2336443
2336444
2336445
2336446
2336447
2882
36009_at
7901460
A_23_P73972
A_24_P418816
GE54767
GO:0003824
GO:0004096
GO:0004601
GO:0004602
GO:0005515
GO:0005576
GO:0005783
GO:0005788
GO:0006979
GO:0016209
GO:0016491
GO:0034599
GO:0043226
GO:0098754
GO:0098869
HMNXSV003013893
Hs.43728.0.S2_3p_at
ILMN_1726030
PH_hs_0003176
TC01000643.hg
Participates
as a member of
Inferred To
GPX7 [endoplasmic reticulum lumen] (Bos taurus)
GPX7 [endoplasmic reticulum lumen] (Canis familiaris)
GPX7 [endoplasmic reticulum lumen] (Danio rerio)
GPX7 [endoplasmic reticulum lumen] (Gallus gallus)
GPX7 [endoplasmic reticulum lumen] (Plasmodium falciparum)
GPX7 [endoplasmic reticulum lumen] (Sus scrofa)
Gpx7 [endoplasmic reticulum lumen] (Mus musculus)
Gpx7 [endoplasmic reticulum lumen] (Rattus norvegicus)
gpx7 [endoplasmic reticulum lumen] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
PDB
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P42858 HTT  1 0.556 3
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