Reactome | MCCC1 [cytosol]

MCCC1 [cytosol]

Stable Identifier

R-HSA-3323164

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

methylcrotonyl-CoA carboxylase alpha chain

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Metabolism (Homo sapiens)

- Metabolism of vitamins and cofactors (Homo sapiens)
  - Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
    - Biotin transport and metabolism (Homo sapiens)
      - HLCS biotinylates 6xMCCC1:6xMCCC2 (Homo sapiens)
        
        6xMCCC1:6xMCCC2 [cytosol] (Homo sapiens)
        
        MCCC1 [cytosol] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
16023992	Mitochondrial targeting signals and mature peptides of 3-methylcrotonyl-CoA carboxylase Holzinger, A, Anslinger, K, Röschinger, W, Roscher, AA, Herrmann, JM, Polanetz, R, Stadler, SC, Meier, S, Mayerhofer, PU	Biochem Biophys Res Commun	2005

External Reference Information

External Reference

UniProt:Q96RQ3 MCCC1

Gene Names

MCCC1, MCCA

Chain

transit peptide:1-41, chain:42-725

Reference Genes

BioGPS Gene:56922 MCCC1

COSMIC (genes):MCCC1 MCCC1

CTD Gene:56922 MCCC1

dbSNP Gene:56922 MCCC1

ENSEMBL:ENSG00000078070.14 MCCC1

HGNC:6936 MCCC1

KEGG Gene (Homo sapiens):56922 MCCC1

Monarch:56922 MCCC1

NCBI Gene:56922 MCCC1

OMIM:609010 MCCC1

UCSC:Q96RQ3 MCCC1

Reference Transcript

Other Identifiers

0000360332

11747553_a_at

11752552_a_at

11754306_a_at

16961989

218440_PM_at

218440_at

2707823

2707825

2707826

2707827

2707829

2707831

2707833

2707836

2707844

2707847

2707848

2707849

2707851

2707853

2707854

2707858

2707859

2707860

2707864

2707865

2707867

2707868

2707870

45026_s_at

52542_at

56922

8092328

A_23_P58036

GE62612

GO:0000166

GO:0002169

GO:0004075

GO:0004485

GO:0005515

GO:0005524

GO:0005622

GO:0005737

GO:0005739

GO:0005759

GO:0005829

GO:0006520

GO:0006552

GO:0006766

GO:0006768

GO:0006790

GO:0009083

GO:0009374

GO:0016874

GO:0032991

GO:0043226

GO:0046872

GO:1905202

HMNXSV003017607

ILMN_1760174

PH_hs_0003377

TC03002053.hg

g13518227_3p_at

Participates

as a component of

6xMCCC1:6xMCCC2 [cytosol] (Homo sapiens)

Other forms of this molecule

Btn-MCCC1 [cytosol]

Btn-MCCC1 [mitochondrial matrix]

Inferred To

Mccc1 [cytosol] (Drosophila melanogaster)

mccc-1 [cytosol] (Caenorhabditis elegans)

MCCC1 [cytosol] (Bos taurus)

MCCC1 [cytosol] (Canis familiaris)

MCCC1 [cytosol] (Danio rerio)

MCCC1 [cytosol] (Dictyostelium discoideum)

MCCC1 [cytosol] (Gallus gallus)

MCCC1 [cytosol] (Mus musculus)

MCCC1 [cytosol] (Rattus norvegicus)

MCCC1 [cytosol] (Sus scrofa)

dcun1d1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001280202.1, NP_064551.3

OpenTargets

ENSG00000078070

GeneCards

Q96RQ3

HPA

ENSG00000078070-MCCC1

Ensembl

ENST00000265594, ENSG00000078070, ENSP00000265594

PRO

Q96RQ3

Pharos - Targets

Q96RQ3

Orphanet

16383

PDB

2EJM

HMDB Protein

HMDBP00510