Reactome | TADA2B [nucleoplasm]

TADA2B [nucleoplasm]

Stable Identifier

R-HSA-3322963

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional adapter 2-beta, TAD2B_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - Ub-specific processing proteases (Homo sapiens)
      - USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA2B [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA2B [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA2B [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q86TJ2 TADA2B

Gene Names

TADA2B, ADA2B

Chain

chain:1-420

Reference Genes

BioGPS Gene:93624 Q86TJ23

COSMIC (genes):TADA2B TADA2B

CTD Gene:93624 Q86TJ23

dbSNP Gene:93624 Q86TJ23

ENSEMBL:ENSG00000173011 TADA2B

HGNC:30781 Q86TJ23

KEGG:hsa:93624 Q86TJ23

Monarch:93624 Q86TJ23

NCBI Gene:93624 Q86TJ23

OMIM:608790 Q86TJ23

UCSC:Q86TJ2 Q86TJ23

Reference Transcript

Participates

as a component of

Inferred To

tada2b [nucleoplasm] (Xenopus tropicalis)

laf2 [nucleoplasm] (Schizosaccharomyces pombe)

Tada2b [nucleoplasm] (Mus musculus)

Tada2b [nucleoplasm] (Rattus norvegicus)

Homologues of TADA2B [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of TADA2B [nucleoplasm] (Schizosaccharomyces pombe)

FUN19 [nucleoplasm] (Saccharomyces cerevisiae)

TADA2B [nucleoplasm] (Bos taurus)

TADA2B [nucleoplasm] (Canis familiaris)

TADA2B [nucleoplasm] (Danio rerio)

TADA2B [nucleoplasm] (Dictyostelium discoideum)

TADA2B [nucleoplasm] (Drosophila melanogaster)

TADA2B [nucleoplasm] (Saccharomyces cerevisiae)

TADA2B [nucleoplasm] (Schizosaccharomyces pombe)

TADA2B [nucleoplasm] (Sus scrofa)

laf1 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

ENSEMBL

ENST00000310074, ENSP00000423181, ENSP00000308022, ENSG00000173011, ENSP00000423947, ENST00000515646, ENST00000512388

OpenTargets

ENSG00000173011

GeneCards

TADA2B

HPA

ENSG00000173011-TADA2B

PRO

Q86TJ2

Pharos - Targets

Q86TJ2

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.725	6
UniProt:Q9Y4A5 TRRAP	1	TRRAP [nucleoplasm] (R-HSA-3322951)	0.643	4
UniProt:Q9NY61 AATF	1	AATF [cytosol] (R-HSA-205071)	0.543	4
UniProt:Q96EB6 SIRT1	1	SIRT1 [nucleoplasm] (R-HSA-427531)	0.527	3
UniProt:O75528 TADA3	1	TADA3 [nucleoplasm] (R-HSA-3322966)	0.527	3
UniProt:O95749 GGPS1	1	GGPS1 [cytosol] (R-HSA-191415)	0.527	2
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.527	2

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