Reactome | TADA2B [nucleoplasm]

TADA2B [nucleoplasm]

Stable Identifier

R-HSA-3322963

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional adapter 2-beta, TAD2B_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - Ub-specific processing proteases (Homo sapiens)
      - USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA2B [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA2B [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA2B [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q86TJ2 TADA2B

Gene Names

TADA2B, ADA2B

Chain

chain:1-420

Reference Genes

BioGPS Gene:93624 TADA2B

COSMIC (genes):TADA2B TADA2B

CTD Gene:93624 TADA2B

dbSNP Gene:93624 TADA2B

ENSEMBL:ENSG00000173011 TADA2B

ENSEMBL_homo_sapiens_GENE:ENSG00000173011.12 TADA2B

HGNC:30781 TADA2B

KEGG Gene (Homo sapiens):93624 TADA2B

Monarch:93624 TADA2B

NCBI Gene:93624 TADA2B

OMIM:608790 TADA2B

UCSC:Q86TJ2 TADA2B

Reference Transcript

Other Identifiers

11733894_x_at

11733895_a_at

11733896_s_at

11755078_a_at

16964791

226240_PM_at

226240_at

236248_3p_x_at

236248_PM_x_at

236248_x_at

2717222

2717223

2717227

2717228

2717229

2717230

2717231

2717232

2717233

2717234

2717235

2717250

46639_at

8093993

84972_at

93624

A_23_P396541

A_24_P687582

GE724084

GO:0000124

GO:0003682

GO:0003713

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006281

GO:0006282

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006357

GO:0008270

GO:0035065

GO:0036211

GO:0043226

GO:0043484

GO:0045893

GO:0046872

GO:0070461

GO:0140110

HMNXSV003000942

Hs.155512.0.A1_3p_at

Hs.6983.0.S1_3p_at

PH_hs_0026433

PH_hs_0036070

TC04000079.hg

Participates

as a component of

Inferred To

tada2b [nucleoplasm] (Xenopus tropicalis)

laf2 [nucleoplasm] (Schizosaccharomyces pombe)

Tada2b [nucleoplasm] (Mus musculus)

Tada2b [nucleoplasm] (Rattus norvegicus)

Homologues of TADA2B [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of TADA2B [nucleoplasm] (Schizosaccharomyces pombe)

FUN19 [nucleoplasm] (Saccharomyces cerevisiae)

TADA2B [nucleoplasm] (Bos taurus)

TADA2B [nucleoplasm] (Canis familiaris)

TADA2B [nucleoplasm] (Danio rerio)

TADA2B [nucleoplasm] (Dictyostelium discoideum)

TADA2B [nucleoplasm] (Drosophila melanogaster)

TADA2B [nucleoplasm] (Saccharomyces cerevisiae)

TADA2B [nucleoplasm] (Schizosaccharomyces pombe)

TADA2B [nucleoplasm] (Sus scrofa)

laf1 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_689506.2, XP_011511897.1

OpenTargets

ENSG00000173011

HPA

ENSG00000173011-TADA2B

GeneCards

Q86TJ2

Ensembl

ENSP00000423181, ENST00000310074, ENSP00000308022, ENST00000515646, ENSP00000423947, ENST00000512388, ENSG00000173011

PRO

Q86TJ2

Pharos - Targets

Q86TJ2

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.643	3
UniProt:Q9NY61 AATF	1	AATF [cytosol] (R-HSA-205071)	0.543	4