Reactome | TRRAP [nucleoplasm]

TRRAP [nucleoplasm]

Stable Identifier

R-HSA-3322951

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transformation/transcription domain-associated protein, TRRAP_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q96ES7 SGF29

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External Reference Information

External Reference

UniProt:Q9Y4A5 TRRAP

Gene Names

TRRAP, PAF400

Chain

initiator methionine:1, chain:2-3859

Reference Genes

BioGPS Gene:8295 TRRAP

COSMIC (genes):TRRAP TRRAP

CTD Gene:8295 TRRAP

dbSNP Gene:8295 TRRAP

ENSEMBL:ENSG00000196367 TRRAP

HGNC:12347 TRRAP

KEGG:hsa:8295 TRRAP

Monarch:8295 TRRAP

NCBI Gene:8295 TRRAP

OMIM:603015 TRRAP

UCSC:Q9Y4A5 TRRAP

Reference Transcript

Participates

as a component of

as an input of

Beta-catenin recruits TRRAP/KAT5 HAT components (Homo sapiens)

Inferred To

trr-1 [nucleoplasm] (Caenorhabditis elegans)

TRA1 [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of TRRAP [nucleoplasm] (Mus musculus)

Ghost homologue of TRRAP [nucleoplasm] (Rattus norvegicus)

tra1 [nucleoplasm] (Dictyostelium discoideum)

tra1 [nucleoplasm] (Schizosaccharomyces pombe)

Nipped-A [nucleoplasm] (Drosophila melanogaster)

TRRAP [nucleoplasm] (Bos taurus)

TRRAP [nucleoplasm] (Canis familiaris)

TRRAP [nucleoplasm] (Gallus gallus)

TRRAP [nucleoplasm] (Sus scrofa)

trrap [nucleoplasm] (Danio rerio)

trrap [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001231509.1, NP_003487.1

Guide to Pharmacology - Targets

2256

ENSEMBL

ENSP00000347733, ENSP00000352925, ENSG00000196367, ENST00000359863, ENST00000355540

OpenTargets

ENSG00000196367

HPA

ENSG00000196367-TRRAP

GeneCards

TRRAP

PRO

Q9Y4A5

Pharos - Targets

Q9Y4A5

GlyGen

Q9Y4A5

PDB

8XVG, 8XVV, 8QRI, 8H7G, 7KTR, 9C47

Interactors (35)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.886	8
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.788	8
UniProt:Q92830 KAT2A	1	KAT2A [nucleoplasm] (R-HSA-3006516)	0.758	6
UniProt:Q9NV56 MRGBP	1	MRGBP [nucleoplasm] (R-HSA-3322953)	0.737	7
UniProt:O15265 ATXN7	2	ATXN7 [cytosol] (R-HSA-201591) ATXN7 [nucleoplasm] (R-HSA-8869458)	0.737	8
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.725	6
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.725	4
UniProt:O75528 TADA3	1	TADA3 [nucleoplasm] (R-HSA-3322966)	0.725	4
UniProt:Q96BN2 TADA1	1	TADA1 [nucleoplasm] (R-HSA-3322965)	0.725	5
UniProt:Q14CW9 ATXN7L3	1	ATXN7L3 [nucleoplasm] (R-HSA-3662285)	0.725	5
UniProt:O96019 ACTL6A	1	ACTL6A [nucleoplasm] (R-HSA-2980912)	0.669	6
UniProt:Q9H0E9 BRD8	1	BRD8 [nucleoplasm] (R-HSA-3321977)	0.669	3
UniProt:Q16514 TAF12	1	TAF12 [nucleoplasm] (R-HSA-65555)	0.643	4
UniProt:Q15906 VPS72	1	VPS72 [nucleoplasm] (R-HSA-3321992)	0.643	3
UniProt:Q86TJ2 TADA2B	1	TADA2B [nucleoplasm] (R-HSA-3322963)	0.643	4
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.643	4
UniProt:Q15014 MORF4L2	1	MORF4L2 [nucleoplasm] (R-HSA-3322945)	0.643	3
UniProt:Q52LR7 EPC2			0.643	4
UniProt:Q9UBU8 MORF4L1	1	MORF4L1 [nucleoplasm] (R-HSA-3321982)	0.643	5
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.558	4
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.527	2
UniProt:O95619 YEATS4	1	YEATS4 [nucleoplasm] (R-HSA-3322940)	0.527	3
UniProt:Q9HAF1 MEAF6	1	MEAF6 [nucleoplasm] (R-HSA-3318448)	0.527	3
UniProt:Q86VZ6 JAZF1			0.527	3
UniProt:Q6PIV2 FOXR1			0.527	3
UniProt:O75486 SUPT3H	1	SUPT3H [nucleoplasm] (R-HSA-3322944)	0.527	2
UniProt:Q9Y6J9 TAF6L	1	TAF6L [nucleoplasm] (R-HSA-212393)	0.527	3
UniProt:Q6PJQ5 FOXR2			0.527	2
UniProt:Q9NPF5 DMAP1	1	DMAP1 [nucleoplasm] (R-HSA-212166)	0.527	3
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.527	2
UniProt:O43156 TTI1			0.527	2
UniProt:Q96A08 H2BC1	9	HIST1H2BA [nucleoplasm] (R-HSA-181916) AcK22-HIST1H2BA [nucleoplasm] (R-HSA-4568647) AcK17-HIST1H2BA [nucleoplasm] (R-HSA-4568631) AcK14-HIST1H2BA [nucleoplasm] (R-HSA-4568615) AcK7-HIST1H2BA [nucleoplasm] (R-HSA-4568624) Ub-122-HIST1H2BA [nucleoplasm] (R-HSA-3364020) HIST1H2BA [extracellular region] (R-HSA-977582) AcK-HIST1H2BA [nucleoplasm] (R-HSA-4549263) Ub-HIST1H2BA [nucleoplasm] (R-HSA-6782561)	0.527	4
UniProt:Q9UPT9 USP22	1	USP22 [nucleoplasm] (R-HSA-3662288)	0.527	3
UniProt:Q9UF02 CCG5			0.527	2
UniProt:Q8NEM7 SUPT20H	1	SUPT20H [nucleoplasm] (R-HSA-3662286)	0.527	3

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