Phosphorylated glycogen synthase 1 (GYS1-b) complexed with oligo-D-glucose-GYG1 catalyzes the polyglucosylation of the latter. (Here the addition of four glucose residues is annotated.) This reaction is allosterically activated by glucose-6-phosphate (G6P) (Cameron et al. 2009; Roach et al. 2012). Glucose-6-phosphate (G6P) activates the phosphorylated ("b") form of GYS1 ("muscle") glycogen synthase (Roach et al. 2012).
Utgikar, R, Robinson, BH, Cameron, JM, Chiasson, D, Halliday, W, Ackerley, CA, Raiman, J, Mackay, N, Levandovskiy, V
Hurley, TD, Roach, PJ, Tagliabracci, VS, DePaoli-Roach, AA
glycogen (starch) synthase activity of oligoGlc-GYG1:GYS1-b tetramer [cytosol]
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