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KAT7 [nucleoplasm]
Stable Identifier
R-HSA-3321823
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone acetyltransferase KAT7, KAT7_HUMAN, HBO1, MYST2
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Homo sapiens)
KAT7:ING4,5 dimers:MEAF6:PHF17,(15,16) [nucleoplasm] (Homo sapiens)
KAT7 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95251 KAT7
Gene Names
KAT7, HBO1, HBOa, MYST2
Chain
chain:1-611
Reference Genes
BioGPS Gene:11143 KAT7
COSMIC (genes):KAT7 KAT7
CTD Gene:11143 KAT7
dbSNP Gene:11143 KAT7
ENSEMBL:ENSG00000136504 KAT7
HGNC:17016 KAT7
KEGG:hsa:11143 KAT7
Monarch:11143 KAT7
NCBI Gene:11143 KAT7
OMIM:609880 KAT7
UCSC:O95251 KAT7
Reference Transcript
RefSeq:NM_001199158.1 KAT7
RefSeq:NM_001199157.1 KAT7
RefSeq:NM_001199156.1 KAT7
RefSeq:NM_007067.4 KAT7
RefSeq:NM_001199155.1 KAT7
Other Identifiers
11143
11732117_s_at
11752292_s_at
11753890_a_at
11757691_a_at
16655499
16655565
16655567
16655569
16655571
16655573
16655575
16655577
16655587
16655589
16655591
16655593
16655595
16655597
16655599
16655601
16655603
16655605
16655607
16655611
16655613
16655615
16655617
16655619
16655621
16655623
16655625
16655627
16655629
16655631
16835615
18671469
18671470
18671471
18671472
18671473
18671474
18671475
18671476
18671477
18671478
18671479
18671480
18671481
18671482
18671483
18671484
18671485
18671486
18671487
18671488
18671489
18671490
200049_PM_at
200049_at
2346621
34231_at
3725783
3725784
3725785
3725786
3725787
3725788
3725789
3725790
3725795
3725796
3725800
3725801
3725802
3725803
3725804
3725805
3725806
3725807
3725808
3725809
3725811
3725812
3725813
3725814
3725815
3725816
3725817
3725818
3725819
3725820
3725821
3725822
3725824
3725956
3725958
3725960
3725962
3725964
3725966
3725968
3725970
3725972
3725974
3725988
3725990
3725992
3725994
3725996
3725998
3726000
3726002
3726004
3726006
3726008
3726010
3726012
3726014
3726016
3726018
3726020
3726022
3726024
3726026
3726028
3726030
3726032
3726034
3726036
3726038
3726040
3726042
3726044
3726045
3726046
3726048
4014908
4014911
4014913
4014915
4014916
65271_s_at
7892566
7892771
7892854
7892892
7892967
7893062
7893169
7893197
7893240
7893254
7893538
7893588
7893668
7893682
7893834
7893879
7893886
7894049
7894226
7894377
7894383
7894462
7894578
7894593
7894635
7894648
7894709
7894715
7894851
7894957
7895302
7895377
7895397
7895434
7895471
7895599
7895701
7895720
7895749
7895765
7895822
7895971
7896009
7896075
7896231
7896259
7896260
7896411
7896499
7896522
7896534
7896546
7896551
7896588
7896600
8008213
80894_at
84317_at
A_14_P108562
A_23_P152818
GE58435
GO:0000123
GO:0000775
GO:0000785
GO:0001558
GO:0001779
GO:0002376
GO:0003677
GO:0003682
GO:0003688
GO:0003712
GO:0003824
GO:0004402
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006260
GO:0006275
GO:0006281
GO:0006325
GO:0006338
GO:0006355
GO:0006357
GO:0008270
GO:0010484
GO:0010485
GO:0016740
GO:0016746
GO:0018393
GO:0030154
GO:0030174
GO:0031098
GO:0032786
GO:0036408
GO:0036409
GO:0043226
GO:0043994
GO:0043995
GO:0043996
GO:0043997
GO:0044016
GO:0045740
GO:0045815
GO:0046872
GO:0051726
GO:0060090
GO:0072708
GO:0072710
GO:0072716
GO:0072720
GO:0072739
GO:0090734
GO:0140096
GO:0140110
GO:0140889
GO:1900182
GO:1902035
GO:2000278
GO:2000819
HMNXSV003000615
HMNXSV003010227
ILMN_1798187
PH_hs_0027598
TC17000648.hg
g5901961_3p_at
p7414
Participates
as a component of
KAT7:ING4,5 dimers:MEAF6:PHF17,(15,16) [nucleoplasm] (Homo sapiens)
Inferred To
Homologues of KAT7 [nucleoplasm]
(Dictyostelium discoideum)
KAT7 [nucleoplasm]
(Bos taurus)
KAT7 [nucleoplasm]
(Caenorhabditis elegans)
KAT7 [nucleoplasm]
(Canis familiaris)
KAT7 [nucleoplasm]
(Dictyostelium discoideum)
KAT7 [nucleoplasm]
(Mus musculus)
KAT7 [nucleoplasm]
(Rattus norvegicus)
KAT7 [nucleoplasm]
(Schizosaccharomyces pombe)
KAT7 [nucleoplasm]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
2667
OpenTargets
ENSG00000136504
ENSEMBL
ENSP00000413415
,
ENSP00000398961
,
ENST00000259021
,
ENSP00000423385
,
ENSP00000516419
,
ENSG00000136504
,
ENST00000706506
,
ENST00000424009
,
ENST00000510819
,
ENSP00000259021
,
ENST00000509773
,
ENST00000454930
,
ENSP00000424577
HPA
ENSG00000136504-KAT7
GeneCards
KAT7
PRO
O95251
Pharos - Targets
O95251
GlyGen
O95251
PDB
6MAK
,
5GK9
,
6MAJ
,
7D0S
,
7D0Q
,
7D0O
,
7D0R
,
7D0P
HMDB Protein
HMDBP11580
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08670 VIM
11
Vimentin [lysosomal lumen]
(R-HSA-9659977)
Vimentin [cytosol]
(R-HSA-9646687)
Vimentin [microtubule organizing center]
(R-HSA-9657898)
Vimentin [late endosome lumen]
(R-HSA-9660019)
VIM [cytosol]
(R-HSA-201600)
VIM(2-259) [cytosol]
(R-HSA-350323)
VIM(260-466) [cytosol]
(R-HSA-350314)
VIM(2-429) [cytosol]
(R-HSA-350317)
VIM(430-466) [cytosol]
(R-HSA-350316)
VIM(86-466) [cytosol]
(R-HSA-350294)
VIM(2-85) [cytosol]
(R-HSA-350264)
0.747
4
UniProt:P53350 PLK1
4
PLK1 [cytosol]
(R-HSA-164603)
p-T210-PLK1 [nucleoplasm]
(R-HSA-3002800)
p-T210-PLK1 [cytosol]
(R-HSA-3000318)
PLK1 [nucleoplasm]
(R-HSA-156720)
0.671
6
UniProt:P10275 AR
4
AR [nucleoplasm]
(R-HSA-446174)
AR [cytosol]
(R-HSA-5618082)
monoSUMO1-K386,520-AR [nucleoplasm]
(R-HSA-4090320)
PolyUb-AR [nucleoplasm]
(R-HSA-6782984)
0.593
5
UniProt:Q96EZ8 MCRS1
1
MCRS1 [nucleoplasm]
(R-HSA-3321849)
0.556
3
UniProt:Q99728 BARD1
13
K6PolyUb,p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-9707286)
p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-5659846)
BARD1 [nucleoplasm]
(R-HSA-5659775)
K6PolyUb-BARD1 [nucleoplasm]
(R-HSA-9701024)
BARD1 C83G [nucleoplasm]
(R-HSA-9699139)
BARD1 C50G [nucleoplasm]
(R-HSA-9699137)
BARD1 L44R [nucleoplasm]
(R-HSA-9699126)
BARD1 H68Y [nucleoplasm]
(R-HSA-9699151)
BARD1 W34R [nucleoplasm]
(R-HSA-9699166)
BARD1 G623W [nucleoplasm]
(R-HSA-9699148)
BARD1 C53W [nucleoplasm]
(R-HSA-9700807)
BARD1 C71Y [nucleoplasm]
(R-HSA-9700808)
BARD1 G623E [nucleoplasm]
(R-HSA-9699135)
0.508
2
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