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SMAD4 MH2 domain mutants [cytosol]
Stable Identifier
R-HSA-3311017
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by TGF-beta Receptor Complex in Cancer (Homo sapiens)
Loss of Function of SMAD4 in Cancer (Homo sapiens)
SMAD4 MH2 Domain Mutants in Cancer (Homo sapiens)
SMAD4 MH2 Domain Mutants do not bind phosphorylated SMAD2 and SMAD3 (Homo sapiens)
SMAD4 MH2 domain mutants [cytosol] (Homo sapiens)
Participants
members
SMAD4 A406T [cytosol]
(Homo sapiens)
SMAD4 D351G [cytosol]
(Homo sapiens)
SMAD4 D351H [cytosol]
(Homo sapiens)
SMAD4 D351Y [cytosol]
(Homo sapiens)
SMAD4 D351del [cytosol]
(Homo sapiens)
SMAD4 K428T [cytosol]
(Homo sapiens)
SMAD4 P356L [cytosol]
(Homo sapiens)
SMAD4 P356R [cytosol]
(Homo sapiens)
SMAD4 R361C [cytosol]
(Homo sapiens)
SMAD4 R361H [cytosol]
(Homo sapiens)
SMAD4 R515T [cytosol]
(Homo sapiens)
candidates
SMAD4 K428R [cytosol]
(Homo sapiens)
SMAD4 R361G [cytosol]
(Homo sapiens)
SMAD4 R361S [cytosol]
(Homo sapiens)
SMAD4 G30* [cytosol]
(Homo sapiens)
SMAD4 E33* [cytosol]
(Homo sapiens)
SMAD4 E49* [cytosol]
(Homo sapiens)
SMAD4 E53* [cytosol]
(Homo sapiens)
SMAD4 Q83* [cytosol]
(Homo sapiens)
SMAD4 Y95* [cytosol]
(Homo sapiens)
SMAD4 E108* [cytosol]
(Homo sapiens)
SMAD4 Q116* [cytosol]
(Homo sapiens)
SMAD4 K122* [cytosol]
(Homo sapiens)
SMAD4 R135* [cytosol]
(Homo sapiens)
SMAD4 S138* [cytosol]
(Homo sapiens)
SMAD4 S144* [cytosol]
(Homo sapiens)
SMAD4 L146* [cytosol]
(Homo sapiens)
SMAD4 G168* [cytosol]
(Homo sapiens)
SMAD4 L172* [cytosol]
(Homo sapiens)
SMAD4 E175* [cytosol]
(Homo sapiens)
SMAD4 Q183* [cytosol]
(Homo sapiens)
SMAD4 Y195* [cytosol]
(Homo sapiens)
SMAD4 E205* [cytosol]
(Homo sapiens)
SMAD4 Q224* [cytosol]
(Homo sapiens)
SMAD4 Q239* [cytosol]
(Homo sapiens)
SMAD4 Q245* [cytosol]
(Homo sapiens)
SMAD4 Q248* [cytosol]
(Homo sapiens)
SMAD4 Q249* [cytosol]
(Homo sapiens)
SMAD4 Q250* [cytosol]
(Homo sapiens)
SMAD4 Q256* [cytosol]
(Homo sapiens)
SMAD4 Q289* [cytosol]
(Homo sapiens)
SMAD4 E307* [cytosol]
(Homo sapiens)
SMAD4 E321* [cytosol]
(Homo sapiens)
SMAD4 E330* [cytosol]
(Homo sapiens)
SMAD4 G352* [cytosol]
(Homo sapiens)
SMAD4 G358* [cytosol]
(Homo sapiens)
SMAD4 E390* [cytosol]
(Homo sapiens)
SMAD4 E417* [cytosol]
(Homo sapiens)
SMAD4 L440* [cytosol]
(Homo sapiens)
SMAD4 C443* [cytosol]
(Homo sapiens)
SMAD4 G473* [cytosol]
(Homo sapiens)
SMAD4 G477* [cytosol]
(Homo sapiens)
SMAD4 G510* [cytosol]
(Homo sapiens)
SMAD4 R515* [cytosol]
(Homo sapiens)
SMAD4 Q516* [cytosol]
(Homo sapiens)
SMAD4 E520* [cytosol]
(Homo sapiens)
SMAD4 W524* [cytosol]
(Homo sapiens)
SMAD4 E526* [cytosol]
(Homo sapiens)
SMAD4 E538* [cytosol]
(Homo sapiens)
SMAD4 Q311* [cytosol]
(Homo sapiens)
SMAD4 Q334* [cytosol]
(Homo sapiens)
SMAD4 Q366* [cytosol]
(Homo sapiens)
SMAD4 Q410* [cytosol]
(Homo sapiens)
SMAD4 Q442* [cytosol]
(Homo sapiens)
SMAD4 R445* [cytosol]
(Homo sapiens)
SMAD4 Q448* [cytosol]
(Homo sapiens)
SMAD4 Q455* [cytosol]
(Homo sapiens)
SMAD4 Q534* [cytosol]
(Homo sapiens)
SMAD4 S154* [cytosol]
(Homo sapiens)
SMAD4 S171* [cytosol]
(Homo sapiens)
SMAD4 S178* [cytosol]
(Homo sapiens)
SMAD4 S242* [cytosol]
(Homo sapiens)
SMAD4 S343* [cytosol]
(Homo sapiens)
SMAD4 W101* [cytosol]
(Homo sapiens)
SMAD4 W268* [cytosol]
(Homo sapiens)
SMAD4 W302* [cytosol]
(Homo sapiens)
SMAD4 W398* [cytosol]
(Homo sapiens)
SMAD4 Y260* [cytosol]
(Homo sapiens)
SMAD4 Y276* [cytosol]
(Homo sapiens)
SMAD4 Y322* [cytosol]
(Homo sapiens)
SMAD4 Y328* [cytosol]
(Homo sapiens)
SMAD4 Y412* [cytosol]
(Homo sapiens)
SMAD4 W509* [cytosol]
(Homo sapiens)
SMAD4 Y430* [cytosol]
(Homo sapiens)
SMAD4 Y513* [cytosol]
(Homo sapiens)
Participates
as an input of
SMAD4 MH2 Domain Mutants do not bind phosphorylated SMAD2 and SMAD3 (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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