Reactome | TAS2R30 [plasma membrane]

TAS2R30 [plasma membrane]

Stable Identifier

R-HSA-3299626

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Taste receptor type 2 member 30, T2R30_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
      - The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
      - T2Rs bind bitter-tasting compounds (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
        
        TAS2Rs [plasma membrane] (Homo sapiens)
        
        TAS2R30 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P59541 TAS2R30

Gene Names

TAS2R30, TAS2R47

Chain

chain:1-319

Reference Genes

BioGPS Gene:259293 TAS2R30

COSMIC (genes):TAS2R30 TAS2R30

CTD Gene:259293 TAS2R30

dbSNP Gene:259293 TAS2R30

ENSEMBL:ENSG00000256188 TAS2R30

HGNC:19112 TAS2R30

KEGG:hsa:259293 TAS2R30

Monarch:259293 TAS2R30

NCBI Gene:259293 TAS2R30

OMIM:613963 TAS2R30

UCSC:P59541 TAS2R30

Reference Transcript

RefSeq:NM_001097643.1 TAS2R30

Other Identifiers

11715255_s_at

11759473_at

16761526

259293

3444389

3444555

3444556

4052189

4053679

4053681

ADDON000035.hg

A_33_P3294951

GO:0001580

GO:0004930

GO:0005886

GO:0007186

GO:0016020

GO:0033038

GO:0050877

GO:0050909

GO:0060089

HMNXSV003037735

TC12001243.hg

TC12002762.hg

Participates

as a member of

as a component of

TAS2R30:ligand [plasma membrane] (Homo sapiens)

Inferred To

TAS2R46 [plasma membrane] (Bos taurus)

Tas2r120 [plasma membrane] (Mus musculus)

Tas2r120 [plasma membrane] (Rattus norvegicus)

Tas2r136 [plasma membrane] (Mus musculus)

Tas2r136 [plasma membrane] (Rattus norvegicus)

t2r14 [plasma membrane] (Xenopus tropicalis)

CAFA-T2R43 [plasma membrane] (Canis familiaris)

TAS2R30 [plasma membrane] (Bos taurus)

t2r2 [plasma membrane] (Xenopus tropicalis)

LOC100154902 [plasma membrane] (Sus scrofa)

t2r3 [plasma membrane] (Xenopus tropicalis)

Homologues of TAS2R30 [plasma membrane] (Bos taurus)

Homologues of TAS2R30 [plasma membrane] (Canis familiaris)

Homologues of TAS2R30 [plasma membrane] (Danio rerio)

Homologues of TAS2R30 [plasma membrane] (Gallus gallus)

Homologues of TAS2R30 [plasma membrane] (Mus musculus)

Homologues of TAS2R30 [plasma membrane] (Rattus norvegicus)

Homologues of TAS2R30 [plasma membrane] (Xenopus tropicalis)

TAS2R7 [plasma membrane] (Gallus gallus)

tas2r200.1 [plasma membrane] (Danio rerio)

tas2r7 [plasma membrane] (Xenopus tropicalis)

TAS2R40 [plasma membrane] (Gallus gallus)

LOC100682759 [plasma membrane] (Canis familiaris)

t2r15 [plasma membrane] (Xenopus tropicalis)

tas2r4 [plasma membrane] (Xenopus tropicalis)

LOC782957 [plasma membrane] (Bos taurus)

tas2r200.2 [plasma membrane] (Danio rerio)

LOC101747503 [plasma membrane] (Gallus gallus)

Cross References

RefSeq

NP_001091112.1

Guide to Pharmacology - Targets

673

ENSEMBL

ENST00000539585, ENST00000576640, ENSG00000262111, ENSG00000256188, ENSP00000444736, ENSP00000458170

OpenTargets

ENSG00000256188

GeneCards

TAS2R30

HPA

ENSG00000256188-TAS2R30

PRO

P59541

Pharos - Targets

P59541

GlyGen

P59541