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TAS2R46 [plasma membrane]
Stable Identifier
R-HSA-3299610
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Taste receptor type 2 member 46, T2R46_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
T2Rs bind bitter-tasting compounds (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R46 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P59540 TAS2R46
Gene Names
TAS2R46
Chain
chain:1-309
Reference Genes
BioGPS Gene:259292 TAS2R46
COSMIC (genes):TAS2R46 TAS2R46
CTD Gene:259292 TAS2R46
dbSNP Gene:259292 TAS2R46
ENSEMBL:ENSG00000226761 TAS2R46
ENSEMBL:ENSG00000262525 TAS2R46
HGNC:18877 TAS2R46
KEGG Gene (Homo sapiens):259292 TAS2R46
Monarch:259292 TAS2R46
NCBI Gene:259292 TAS2R46
OMIM:612774 TAS2R46
UCSC:P59540 TAS2R46
Reference Transcript
RefSeq:NM_176887.2 TAS2R46
Other Identifiers
0002370592
11742393_at
11742394_x_at
16761521
259292
3444526
3444527
3444556
7961293
A_23_P376114
GE903053
GO:0001580
GO:0003674
GO:0004930
GO:0005575
GO:0005886
GO:0005929
GO:0007165
GO:0007186
GO:0008150
GO:0016020
GO:0016021
GO:0033038
GO:0042995
GO:0043226
GO:0050877
GO:0050896
GO:0050909
GO:0060170
ILMN_1811572
TC12001240.hg
Participant Of
hasMember
TAS2Rs [plasma membrane]
Inferred To
Tas2r120 [plasma membrane] (Mus musculus)
Tas2r120 [plasma membrane] (Rattus norvegicus)
t2r34 [plasma membrane] (Xenopus tropicalis)
tas2r8 [plasma membrane] (Xenopus tropicalis)
t2r37 [plasma membrane] (Xenopus tropicalis)
Tas2r136 [plasma membrane] (Mus musculus)
Tas2r136 [plasma membrane] (Rattus norvegicus)
t2r14 [plasma membrane] (Xenopus tropicalis)
t2r9 [plasma membrane] (Xenopus tropicalis)
CAFA-T2R43 [plasma membrane] (Canis familiaris)
Homologues of TAS2R20 [plasma membrane] (Bos taurus)
Homologues of TAS2R20 [plasma membrane] (Danio rerio)
Homologues of TAS2R20 [plasma membrane] (Gallus gallus)
Homologues of TAS2R20 [plasma membrane] (Mus musculus)
Homologues of TAS2R20 [plasma membrane] (Rattus norvegicus)
Homologues of TAS2R20 [plasma membrane] (Xenopus tropicalis)
TAS2R7 [plasma membrane] (Gallus gallus)
rnf167 [plasma membrane] (Xenopus tropicalis)
t2r32 [plasma membrane] (Xenopus tropicalis)
t2r52 [plasma membrane] (Xenopus tropicalis)
t2r45 [plasma membrane] (Xenopus tropicalis)
t2r48 [plasma membrane] (Xenopus tropicalis)
tas2r200.2 [plasma membrane] (Danio rerio)
TAS2R46 [plasma membrane] (Bos taurus)
TAS2R20 [plasma membrane] (Bos taurus)
TAS2R20 [plasma membrane] (Gallus gallus)
TAS2R20 [plasma membrane] (Xenopus tropicalis)
hcn4 [plasma membrane] (Xenopus tropicalis)
t2r46 [plasma membrane] (Xenopus tropicalis)
LOC100154902 [plasma membrane] (Sus scrofa)
t2r10 [plasma membrane] (Xenopus tropicalis)
t2r20 [plasma membrane] (Xenopus tropicalis)
t2r53 [plasma membrane] (Xenopus tropicalis)
t2r43 [plasma membrane] (Xenopus tropicalis)
itk [plasma membrane] (Xenopus tropicalis)
slc38a10 [plasma membrane] (Xenopus tropicalis)
tas2r200.1 [plasma membrane] (Danio rerio)
tas2r7 [plasma membrane] (Xenopus tropicalis)
tas2r13 [plasma membrane] (Xenopus tropicalis)
TAS2R40 [plasma membrane] (Gallus gallus)
tas2r203 [plasma membrane] (Danio rerio)
LOC782957 [plasma membrane] (Bos taurus)
znf592 [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_795368.2
OpenTargets
ENSG00000226761
GeneCards
P59540
HPA
ENSG00000226761-TAS2R46
Ensembl
ENST00000574263
,
ENSP00000436450
,
ENST00000533467
,
ENSG00000226761
,
ENSP00000460229
,
ENSG00000262525
PRO
P59540
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