Reactome | HSPH1 [cytosol]

HSPH1 [cytosol]

Stable Identifier

R-HSA-3299412

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Heat shock protein 105 kDa, HS105_HUMAN, HSP110

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q92598 HSPH1

Gene Names

HSPH1, HSP105, HSP110, KIAA0201

Chain

initiator methionine:, chain:2-858

Reference Genes

BioGPS Gene:10808 HSPH1

COSMIC (genes):HSPH1 HSPH1

CTD Gene:10808 HSPH1

dbSNP Gene:10808 HSPH1

ENSEMBL:ENSG00000120694 HSPH1

HGNC:16969 HSPH1

KEGG:hsa:10808 HSPH1

Monarch:10808 HSPH1

NCBI Gene:10808 HSPH1

OMIM:610703 HSPH1

UCSC:Q92598 HSPH1

Reference Transcript

Other Identifiers

10808

11717096_a_at

11747105_a_at

11748072_a_at

11749659_s_at

11753964_x_at

11755205_a_at

11755206_x_at

11758639_s_at

16777896

206976_PM_s_at

206976_s_at

208744_PM_x_at

208744_x_at

235573_PM_at

235573_at

34398_at

3508354

3508355

3508356

3508357

3508358

3508359

3508360

3508361

3508362

3508363

3508364

3508365

3508366

3508367

3508368

3508369

3508371

3508372

3508373

3508375

3508377

3508379

3508380

3508383

3508384

3508385

3508386

3508387

3508388

3508389

3508390

3508391

3508393

3508396

3508399

3508400

3508401

3508402

3508403

3508404

3508405

3508406

75954_at

7970864

A_23_P88119

A_24_P934522

A_33_P3348752

D86956_at

GE81663

GO:0000774

GO:0005515

GO:0005524

GO:0005576

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005874

GO:0006457

GO:0006986

GO:0008092

GO:0032991

GO:0043014

GO:0043226

GO:0044183

GO:0045345

GO:0051085

GO:0051135

GO:0070062

GO:0071682

GO:0098772

GO:0140657

GO:0140662

HMNXSV003046243

Hs.201615.0.A1_3p_at

Hs.36927.1.S1_3p_a_at

Hs.36927.1.S1_3p_x_at

ILMN_1712888

PH_hs_0002918

PH_hs_0031157

TC13000539.hg

g5729878_3p_a_at

Participates

as a member of

HSP70 NEFs [cytosol] (Homo sapiens)

Other forms of this molecule

HSPH1 [endocytic vesicle lumen]

HSPH1 [extracellular region]

Inferred To

Hsph1 [cytosol] (Mus musculus)

Hsph1 [cytosol] (Rattus norvegicus)

hspH [cytosol] (Dictyostelium discoideum)

SSE1 [cytosol] (Saccharomyces cerevisiae)

hsp-110 [cytosol] (Caenorhabditis elegans)

pss1 [cytosol] (Schizosaccharomyces pombe)

HSPH1 [cytosol] (Bos taurus)

HSPH1 [cytosol] (Canis familiaris)

HSPH1 [cytosol] (Plasmodium falciparum)

HSPH1 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENST00000630972, ENST00000320027, ENSP00000318687, ENSP00000487365, ENSP00000369768, ENST00000380405

OpenTargets

ENSG00000120694

HPA

ENSG00000120694-HSPH1

PRO

Q92598

Pharos - Targets

Q92598

GlyGen

Q92598

PDB

6GFA

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11021 HSPA5	6	HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [extracellular region] (R-HSA-351322)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	14
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.471	2

Cite Us!