HCAR1 binds LACT

Stable Identifier
R-HSA-3296326
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
HCAR1 binds L-lactate
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HCAR1 (GPR81) binds L-lactate (2-hydroxy-propanoic acid) (Cai et al. 2008).

Literature References
PubMed ID Title Journal Year
19047060 Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81

Liu, C, Wu, J, Zhu, J, Kuei, C, Yu, J, Shelton, J, Sutton, SW, Li, X, Yun, SJ, Mirzadegan, T, Mazur, C, Kamme, F, Lovenberg, TW

J. Biol. Chem. 2009
18952058 Role of GPR81 in lactate-mediated reduction of adipose lipolysis

Cai, TQ, Ren, N, Jin, L, Cheng, K, Kash, S, Chen, R, Wright, SD, Taggart, AK, Waters, MG

Biochem. Biophys. Res. Commun. 2008
Participants
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