SUCNR1 binds SUCCA

Stable Identifier
R-HSA-3296244
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
SUCNR1 binds succinate
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SUCNR1 (GPR91) is activated by the citric acid cycle intermediate succinate (SUCCA) (He et al. 2004), signalling via Gi to have a role in the stimulation of hematopoietic progenitor cell (HPC) growth (Hakak et al. 2009).

Literature References
PubMed ID Title Journal Year
15141213 Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

He, W, Miao, FJ, Lin, DC, Schwandner, RT, Wang, Z, Gao, J, Chen, JL, Tian, H, Ling, L

Nature 2004
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