pS-172,K48polyUb-TBK1

Stable Identifier
R-HSA-3249397
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TBK1, NAK
Chain
chain:1-729
Other Identifiers
0006380286
11717931_at
11717932_at
16753498
218520_at
29110
3419850
3419853
3419854
3419855
3419856
3419858
3419861
3419865
3419866
3419867
3419870
3419871
3419872
3419873
3419874
3419875
3419877
3419879
3419881
3419882
3419883
3419884
3419885
3419887
3419889
3419890
3419891
45797
4EFO
4EUT
4EUU
4IM0
4IM2
4IM3
4IW0
4IWO
4IWP
4IWQ
5EOA
5EOF
5EP6
60211
63819_at
7956795
A_14_P113016
A_23_P44768
AAF05989
AAF69106
AAH34950
AF174536
AF191838
AK002192
AK291039
BAA92129
BAF83728
BC034950
CCDS8968
CH471054
EAW97133
ENSG00000183735
ENSP00000329967
ENST00000331710
EntrezGene:29110
F5GZI4
F5H1A3
F5H206
g7019546_3p_at
GE58505
GO:0000166
GO:0002218
GO:0002376
GO:0003674
GO:0003676
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005829
GO:0006464
GO:0006468
GO:0006914
GO:0006950
GO:0006954
GO:0007165
GO:0007249
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0009058
GO:0009615
GO:0010008
GO:0010629
GO:0016032
GO:0016235
GO:0016239
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0031410
GO:0032479
GO:0032480
GO:0032481
GO:0032606
GO:0032727
GO:0032728
GO:0033138
GO:0034641
GO:0035666
GO:0042802
GO:0043123
GO:0043167
GO:0043226
GO:0044403
GO:0044565
GO:0045087
GO:0045359
GO:0045944
GO:0050830
GO:0051219
GO:0051607
GO:0071345
GO:1901214
GO:1904417
HGNC:11584
HPA045797
HPA060211
ILMN_1739967
IPR000719
IPR011009
IPR017441
MIM:604834
MIM:616439
MIM:617900
NM_013254
NP_037386
PF00069
PH_hs_0025240
SM00220
TBK1
TBK1-201
TC12000570.hg
uc001ssc.3
UPI0000035B47
XM_005268809
XM_005268810
XP_005268866
XP_005268867
XR_001748674
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 670
Coordinate
670
Modification
K48polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
O-phospho-L-serine at 172
Coordinate
172
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ZINC - World Drugs
ZINC - FDA approved
ZINC - Substances
GeneCards
ZINC target
PRO
BRENDA (Homo sapiens)
ZINC - Predictions - Purchasable
Orphanet
Interactors (38)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q92844 TANK  2 0.906 11
 UniProt:Q14653 IRF3  4 0.886 9
 UniProt:Q86WV6 TMEM173  5 0.862 8
 UniProt:A7MCY6 TBKB1      0.816 8
 UniProt:Q96CV9 OPTN  4 0.796 12
 UniProt:Q12933 TRAF2  5 0.77 4
 UniProt:Q9H6S1 AZI2      0.758 6
 UniProt:Q8IUC6 TICAM1  4 0.688 3
 UniProt:Q14164 IKBKE  5 0.669 5
 UniProt:Q9UHD2 TBK1  6 0.609 2
 UniProt:Q9Y6K9 IKBKG  12 0.609 2
 UniProt:P08238 HSP90AB1  5 0.589 3
 UniProt:P42226 STAT6  6 0.577 7
 UniProt:Q13137 CACO2      0.576 5
 UniProt:P27958-PRO_0000037573      0.571 4
 UniProt:Q7Z434 MAVS  2 0.564 2
 UniProt:P04406 GAPDH  1 0.564 2
 UniProt:I0DF37 I0DF37      0.556 3
 UniProt:Q05127 VP35      0.544 2
 UniProt:O95801 TTC4      0.537 5
 UniProt:I6W9F2 I6W9F2      0.537 6
 UniProt:P27958-PRO_0000037572      0.524 2
 UniProt:K7Y1A2 K7Y1A2      0.524 2
 UniProt:Q92985 IRF7  5 0.508 2
 UniProt:CYorf15B CY15B      0.499 2
 UniProt:Q6DT37 MRCKG      0.499 2
 UniProt:Q9Y6W8 ICOS      0.499 5
 UniProt:Q9UKV8 AGO2  2 0.499 2
 UniProt:Q9NVV4 PAPD1      0.499 2
 UniProt:Q86YT6 MIB1  1 0.499 2
 UniProt:Q7Z3C6 ATG9A  1 0.499 2
 UniProt:Q8BHN1 TXLNG      0.499 2
 UniProt:Q96AX9 MIB2  1 0.499 2
 UniProt:O14730 RIOK3  1 0.499 3
 UniProt:P40222 TXLNA  1 0.499 4
 UniProt:O41932 O41932      0.488 4
 UniProt:F1BA49 F1BA49      0.463 4
 UniProt:Q96NL6 SCLT1  1 0.462 2