Retromer recycles WLS to the Golgi

Stable Identifier
R-HSA-3247836
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Golgi membrane, early endosome membrane
ReviewStatus
5/5
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Retromer recycles WLS to the Golgi
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Retromer is believed to escort WLS from the early endosome back to the Golgi for subsequent rounds of WNT secretion (reviewed in Johannes and Wunder, 2011; Willert and Nusse, 2012 ).

Literature References
PubMed ID Title Journal Year
22952392 Wnt proteins

Nusse, R, Willert, K

Cold Spring Harb Perspect Biol 2012
21725318 The SNXy flavours of endosomal sorting

Wunder, C, Johannes, L

Nat. Cell Biol. 2011
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Orthologous Events
Retromer recycles WLS to the Golgi (Bos taurus)
Retromer recycles WLS to the Golgi (Caenorhabditis elegans)
Retromer recycles WLS to the Golgi (Canis familiaris)
Retromer recycles WLS to the Golgi (Danio rerio)
Retromer recycles WLS to the Golgi (Dictyostelium discoideum)
Retromer recycles WLS to the Golgi (Drosophila melanogaster)
Retromer recycles WLS to the Golgi (Gallus gallus)
Retromer recycles WLS to the Golgi (Mus musculus)
Retromer recycles WLS to the Golgi (Rattus norvegicus)
Retromer recycles WLS to the Golgi (Saccharomyces cerevisiae)
Retromer recycles WLS to the Golgi (Schizosaccharomyces pombe)
Retromer recycles WLS to the Golgi (Sus scrofa)
Retromer recycles WLS to the Golgi (Xenopus tropicalis)
Authored
Rothfels, K  (2013-04-06)
Reviewed
Boutros, M  (2013-05-24)
Created
Rothfels, K  (2013-04-06)
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