TREX1:viral DNA [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-3244619
Type
Complex
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
endoplasmic reticulum membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
22071149 Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease

Perrino, FW, Bailey, SL, Hollis, T, Harvey, S

DNA Repair (Amst.) 2012
20871604 The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

Lieberman, J, Yan, N, Regalado-Magdos, AD, Lee-Kirsch, MA, Stiggelbout, B

Nat. Immunol. 2010
Participants
components
Participates
as an output of
as an input of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
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