Reactome | TFAP2B [nucleoplasm]

TFAP2B [nucleoplasm]

Stable Identifier

R-HSA-3234060

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor AP-2-beta, AP2B_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - SUMOylation (Homo sapiens)
    - SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
      - SUMOylation of transcription factors (Homo sapiens)
        
        SUMOylation of TFAP2B with SUMO1 (Homo sapiens)
        
        TFAP2B homodimer [nucleoplasm] (Homo sapiens)
        
        TFAP2B [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q92481 TFAP2B

Gene Names

TFAP2B

Chain

chain:1-460

Reference Genes

BioGPS Gene:7021 TFAP2B

COSMIC (genes):TFAP2B TFAP2B

CTD Gene:7021 TFAP2B

dbSNP Gene:7021 TFAP2B

ENSEMBL:ENSG00000008196 TFAP2B

HGNC:11743 TFAP2B

KEGG:hsa:7021 TFAP2B

Monarch:7021 TFAP2B

NCBI Gene:7021 TFAP2B

OMIM:601601 TFAP2B

UCSC:Q92481 TFAP2B

Reference Transcript

Other Identifiers

11733305_a_at

11733306_a_at

11733307_at

1553394_PM_a_at

1553394_a_at

17009545

214451_PM_at

214451_at

215686_PM_x_at

215686_x_at

2909949

2909950

2909951

2909952

2909953

2909955

2909956

2909962

2909963

2909964

2909967

2909968

2909969

2909973

2909974

2909976

2909977

2909978

2909979

2909980

2909981

2909982

2909983

2909984

2909985

2909986

2909987

2909988

2909989

2909990

39668_at

7021

8120194

A_24_P20954

A_33_P3317163

GE60178

GO:0000122

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0000987

GO:0001228

GO:0001822

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005975

GO:0006006

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0007423

GO:0008284

GO:0008285

GO:0009410

GO:0010467

GO:0010842

GO:0012501

GO:0030154

GO:0030510

GO:0035136

GO:0035137

GO:0035909

GO:0042127

GO:0042803

GO:0043066

GO:0043226

GO:0043524

GO:0043525

GO:0043565

GO:0043588

GO:0045444

GO:0045595

GO:0045892

GO:0045893

GO:0045944

GO:0046982

GO:0048485

GO:0048745

GO:0048856

GO:0050796

GO:0051402

GO:0072017

GO:0072044

GO:0072210

GO:0097070

GO:0140110

GO:1990837

HMNXSV003046942

HMNXSV003053258

Hs.33102.0.S1_3p_at

Hs.33102.1.S1_3p_s_at

Hs2.33102.1.S1_3p_s_at

ILMN_1758404

ILMN_1853592

PH_hs_0002784

TC06000647.hg

Y09912_rna1_at

Participates

as a component of

as an input of

TFAP2A binds TFAP2B (Homo sapiens)

as a candidate of

TFAP2A,(TFAP2B,TFAP2C) [nucleoplasm] (Homo sapiens)

as a member of

TFAP2 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

monoSUMO1-K21-TFAP2B [nucleoplasm]

Inferred To

TFAP2B [nucleoplasm] (Bos taurus)

TFAP2B [nucleoplasm] (Canis familiaris)

TFAP2B [nucleoplasm] (Gallus gallus)

TFAP2B [nucleoplasm] (Sus scrofa)

Tfap2b [nucleoplasm] (Mus musculus)

Tfap2b [nucleoplasm] (Rattus norvegicus)

Homologues of TFAP2B [nucleoplasm] (Caenorhabditis elegans)

aptf-2 [nucleoplasm] (Caenorhabditis elegans)

tfap2b [nucleoplasm] (Xenopus tropicalis)

aptf-1 [nucleoplasm] (Caenorhabditis elegans)

TfAP-2 [nucleoplasm] (Drosophila melanogaster)

aptf-4 [nucleoplasm] (Caenorhabditis elegans)

aptf-3 [nucleoplasm] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSG00000008196, ENST00000393655, ENSP00000377265

OpenTargets

ENSG00000008196

GeneCards

TFAP2B

HPA

ENSG00000008196-TFAP2B

PRO

Q92481

Pharos - Targets

Q92481

GlyGen

Q92481

Orphanet

TFAP2B

PDB

8J0Q

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q8TAP4-4 LMO3			0.556	3
UniProt:Q15047-2 SETDB1			0.556	3

Cite Us!