CALM1:Ca2+ binds CNG channel

Stable Identifier
R-HSA-3229181
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
Calmodulin:Ca2+ lowers CNG channel sensitivity to cGMP
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As the channels reopen, rising Ca2+ levels result in binding of Ca2+ to calmodulin (CALM1). By targeting the beta subunit of the channel, CALM1:Ca2+ reduces the apparent affinity of the channel for cGMP (Chen et al. 1994, Hsu & Molday 1993, Hsu & Molday 1994).

Participants
Participant Of
This event is regulated
Positively by
Orthologous Events
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Created