p-MAPKAPK3 phosphorylates BMI1

Stable Identifier
R-HSA-3229102
Type
Reaction [transition]
Species
Homo sapiens
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In response to stress-activated p38 signaling, MAPKAPK3 phosphorylates BMI1, leading to the dissociation of the PRC1.4 complex from chromatin and transcription of p14-ARF (Voncken et al. 2005).

Literature References
PubMed ID Title Journal Year
15563468 MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1

Voncken, JW, Niessen, H, Neufeld, B, Rennefahrt, U, Dahlmans, V, Kubben, N, Holzer, B, Ludwig, S, Rapp, UR

J. Biol. Chem. 2005
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Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of phospho-MAPK p38:p-MAPKAPK3 [nucleoplasm]
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Activity
Orthologous Events
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