BANP binds TP53

Stable Identifier
R-HSA-3221982
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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BANP (SMAR1) binds TP53 (p53) and is implicated in both positive (Kaul et al. 2003, Jalota et al. 2005) and negative regulation of TP53 transcriptional activity (Pavithra et al. 2009, Sinha et al. 2010).

Literature References
PubMed ID Title Journal Year
19303885 SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription

Pavithra, L, Mukherjee, S, Sreenath, K, Kar, S, Sakaguchi, K, Roy, S, Chattopadhyay, S

J. Mol. Biol. 2009
15701641 Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine-rich motif

Jalota, A, Singh, K, Pavithra, L, Kaul-Ghanekar, R, Jameel, S, Chattopadhyay, S

J. Biol. Chem. 2005
20075864 Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element

Sinha, S, Malonia, SK, Mittal, SP, Singh, K, Kadreppa, S, Kamat, R, Mukhopadhyaya, R, Pal, JK, Chattopadhyay, S

EMBO J. 2010
12494467 Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice

Kaul, R, Mukherjee, S, Ahmed, F, Bhat, MK, Chhipa, R, Galande, S, Chattopadhyay, S

Int. J. Cancer 2003
Participants
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Orthologous Events
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