BANP binds TP53

Stable Identifier
Reaction [binding]
Homo sapiens
Locations in the PathwayBrowser
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BANP (SMAR1) binds TP53 (p53) and is implicated in both positive (Kaul et al. 2003, Jalota et al. 2005) and negative regulation of TP53 transcriptional activity (Pavithra et al. 2009, Sinha et al. 2010).

Literature References
PubMed ID Title Journal Year
15701641 Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine-rich motif

Jalota, A, Pavithra, L, Kaul-Ghanekar, R, Singh, K, Jameel, S, Chattopadhyay, S

J. Biol. Chem. 2005
19303885 SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription

Sakaguchi, K, Sreenath, K, Mukherjee, S, Pavithra, L, Roy, S, Kar, S, Chattopadhyay, S

J. Mol. Biol. 2009
20075864 Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element

Mukhopadhyaya, R, Mittal, SP, Pal, JK, Sinha, S, Kamat, R, Singh, K, Chattopadhyay, S, Malonia, SK, Kadreppa, S

EMBO J. 2010
12494467 Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice

Bhat, MK, Chhipa, R, Galande, S, Kaul, R, Chattopadhyay, S, Ahmed, F, Mukherjee, S

Int. J. Cancer 2003
Orthologous Events
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