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USP28 [nucleoplasm]
Stable Identifier
R-HSA-3215039
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin carboxyl-terminal hydrolase 28, Deubiquitinating enzyme 28, Ubiquitin thioesterase 28, Ubiquitin-specific-processing protease 28, KIAA1515
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP28 deubiquitinates CLSPN and MYC (Homo sapiens)
USP28 [nucleoplasm] (Homo sapiens)
USP28:CLSPN,MYC [nucleoplasm] (Homo sapiens)
USP28 [nucleoplasm] (Homo sapiens)
USP28:PolyUb-CLSPN, PolyUb-MYC [nucleoplasm] (Homo sapiens)
USP28 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96RU2 USP28
Gene Names
USP28, KIAA1515
Chain
chain:1-1077
Reference Genes
BioGPS Gene:57646 USP28
COSMIC (genes):USP28 USP28
CTD Gene:57646 USP28
dbSNP Gene:57646 USP28
ENSEMBL:ENSG00000048028 USP28
HGNC:12625 USP28
Monarch:57646 USP28
NCBI Gene:57646 USP28
OMIM:610748 USP28
UCSC:Q96RU2 USP28
Reference Transcript
RefSeq:NM_001346258.1 USP28
RefSeq:NM_001346273.1 USP28
RefSeq:NM_020886.3 USP28
Other Identifiers
11728817_x_at
11728818_a_at
11748720_a_at
11752525_a_at
1552678_PM_a_at
1552678_a_at
16744524
230623_3p_x_at
230623_PM_x_at
230623_x_at
231837_PM_at
231837_at
3391815
3391817
3391818
3391819
3391820
3391821
3391823
3391824
3391825
3391826
3391827
3391828
3391829
3391830
3391831
3391832
3391833
3391834
3391835
3391836
3391837
3391838
3391841
3391845
3391846
3391847
3391848
3391849
3391850
3391851
3391852
3391854
3391855
3391856
3391858
3391860
3391862
3391863
3391866
3391867
3391868
3391869
57646
62238_at
71447_at
7951752
A_23_P203075
A_33_P3672482
GE61517
GO:0000077
GO:0003824
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006281
GO:0006508
GO:0006974
GO:0008234
GO:0008283
GO:0010212
GO:0016579
GO:0016604
GO:0016787
GO:0031647
GO:0032991
GO:0034644
GO:0042771
GO:0043226
GO:0071947
GO:0101005
GO:0140096
HMNXSV003023706
Hs.142856.0.A1_3p_a_at
Hs.142856.0.A1_3p_at
Hs.142856.1.A1_3p_at
Hs2.142856.1.S1_3p_s_at
ILMN_1794306
ILMN_1887168
TC11002307.hg
Participates
as a component of
USP28:CLSPN,MYC [nucleoplasm] (Homo sapiens)
USP28:PolyUb-CLSPN, PolyUb-MYC [nucleoplasm] (Homo sapiens)
Inferred To
ubp5 [nucleoplasm]
(Schizosaccharomyces pombe)
UBP2 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of USP28 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of USP28 [nucleoplasm]
(Schizosaccharomyces pombe)
Usp28 [nucleoplasm]
(Mus musculus)
Usp28 [nucleoplasm]
(Rattus norvegicus)
UBP15 [nucleoplasm]
(Saccharomyces cerevisiae)
ubp15 [nucleoplasm]
(Schizosaccharomyces pombe)
USP28 [nucleoplasm]
(Bos taurus)
USP28 [nucleoplasm]
(Canis familiaris)
USP28 [nucleoplasm]
(Gallus gallus)
USP28 [nucleoplasm]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000445743
,
ENST00000537706
,
ENSP00000003302
,
ENST00000003302
OpenTargets
ENSG00000048028
IntEnz
3.4.19.12
HPA
ENSG00000048028-USP28
PRO
Q96RU2
Pharos - Targets
Q96RU2
GlyGen
Q96RU2
HMDB Protein
HMDBP11577
PDB
6HEJ
,
6HEI
,
8P1P
,
8P14
,
2MUU
,
7TUO
,
6H4I
,
8HJE
,
6H4H
,
8P1Q
,
6HEH
,
6HEK
,
8P19
,
2LVA
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12888 TP53BP1
3
TP53BP1 [nucleoplasm]
(R-HSA-61175)
p-S25,S1778-TP53BP1 [nucleoplasm]
(R-HSA-5683418)
monoSUMO1-K-TP53BP1 [nucleoplasm]
(R-HSA-2997591)
0.483
2
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