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KDM2A [nucleoplasm]
Stable Identifier
R-HSA-3214392
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Lysine-specific demethylase 2A ecNumber1.14.11.27/ecNumber, KDM2A_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HDMs demethylate histones (Homo sapiens)
KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Homo sapiens)
KDM2A, KDM2B, KDM4A [nucleoplasm] (Homo sapiens)
KDM2A [nucleoplasm] (Homo sapiens)
KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Homo sapiens)
KDM2A, KDM2B, KDM4A [nucleoplasm] (Homo sapiens)
KDM2A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y2K7 KDM2A
Gene Names
KDM2A, CXXC8, FBL11, FBL7, FBXL11, JHDM1A, KIAA1004
Chain
chain:1-1162
Reference Genes
BioGPS Gene:22992 KDM2A
COSMIC (genes):KDM2A KDM2A
CTD Gene:22992 KDM2A
dbSNP Gene:22992 KDM2A
ENSEMBL:ENSG00000173120 KDM2A
HGNC:13606 KDM2A
Monarch:22992 KDM2A
NCBI Gene:22992 KDM2A
OMIM:605657 KDM2A
UCSC:Q9Y2K7 KDM2A
Reference Transcript
RefSeq:NM_012308.2 KDM2A
RefSeq:NM_001256405.1 KDM2A
RefSeq:XM_011544861.1 KDM2A
Other Identifiers
11717166_a_at
11717167_a_at
16727659
208987_PM_s_at
208987_s_at
208988_PM_at
208988_at
208989_3p_s_at
208989_PM_s_at
208989_s_at
22992
33360_at
3336697
3336698
3336699
3336700
3336706
3336709
3336710
3336711
3336720
3336721
3336722
3336723
3336724
3336726
3336744
3336745
3336751
3336752
3336753
3336754
3336755
3336756
3336757
3336758
3336759
3336760
3336761
3336762
3336764
3336767
3336770
3336771
3336773
3336774
3336775
3336776
3336777
3336778
3336780
3336781
3336782
3336783
3336784
3336785
3336786
3336787
3336788
3336789
3336790
3336792
3336793
3336794
3336795
3336796
46521_r_at
70243_at
7941769
A_14_P108928
A_14_P127433
A_14_P131974
A_23_P83917
GE61949
GO:0003677
GO:0003712
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006281
GO:0006303
GO:0006325
GO:0006338
GO:0006355
GO:0006357
GO:0008168
GO:0008270
GO:0010944
GO:0016491
GO:0016740
GO:0032259
GO:0032452
GO:0032922
GO:0042752
GO:0043226
GO:0045322
GO:0046872
GO:0048511
GO:0051213
GO:0051864
GO:0060090
GO:0140096
GO:0140110
GO:0140680
GO:0141052
HMNXSV003017902
Hs.219614.0.S1_3p_a_at
Hs.219614.0.S3_3p_at
PH_hs_0012401
PH_hs_0040588
TC11000680.hg
TC11002734.hg
g5917729_3p_a_at
Participates
as a member of
KDM2A, KDM2B, KDM4A [nucleoplasm] (Homo sapiens)
Inferred To
Kdm2a [nucleoplasm]
(Rattus norvegicus)
KDM2A [nucleoplasm]
(Bos taurus)
KDM2A [nucleoplasm]
(Caenorhabditis elegans)
KDM2A [nucleoplasm]
(Canis familiaris)
KDM2A [nucleoplasm]
(Mus musculus)
KDM2A [nucleoplasm]
(Schizosaccharomyces pombe)
KDM2A [nucleoplasm]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
2671
ENSEMBL
ENSP00000381640
,
ENSP00000432786
,
ENST00000398645
,
ENSP00000435776
,
ENST00000529006
,
ENST00000530342
OpenTargets
ENSG00000173120
ZINC - Substances
KDM2A_HUMAN
ZINC - Biogenic
KDM2A_HUMAN
ZINC target
Q9Y2K7
PRO
Q9Y2K7
GlyGen
Q9Y2K7
PDB
6C16
,
7UV9
,
2YU1
,
2YU2
,
6BYH
,
4BBQ
ZINC - Metabolites
KDM2A_HUMAN
HPA
ENSG00000173120-KDM2A
Pharos - Targets
Q9Y2K7
ZINC - Predictions - Purchasable
KDM2A_HUMAN
HMDB Protein
HMDBP09184
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63208 SKP1
2
SKP1 [cytosol]
(R-HSA-174150)
SKP1 [nucleoplasm]
(R-HSA-187538)
0.744
6
UniProt:Q13257 MAD2L1
2
Activated MAD2L1 [cytosol]
(R-HSA-141447)
MAD2L1 [cytosol]
(R-HSA-141400)
0.527
3
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