Reactome | MCOLN3 [plasma membrane]

MCOLN3 [plasma membrane]

Stable Identifier

R-HSA-3211773

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Mucolipin-3, MCLN3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8TDD5 MCOLN3

Gene Names

MCOLN3

Chain

chain:1-553

Reference Genes

BioGPS Gene:55283 MCOLN3

COSMIC (genes):MCOLN3 MCOLN3

CTD Gene:55283 MCOLN3

dbSNP Gene:55283 MCOLN3

ENSEMBL:ENSG00000055732 MCOLN3

HGNC:13358 MCOLN3

KEGG:hsa:55283 MCOLN3

Monarch:55283 MCOLN3

NCBI Gene:55283 MCOLN3

OMIM:607400 MCOLN3

UCSC:Q8TDD5 MCOLN3

Reference Transcript

Other Identifiers

11746600_a_at

11755444_a_at

11760495_a_at

1557292_PM_a_at

1557292_a_at

16689020

220484_PM_at

220484_at

229797_PM_at

229797_at

2420682

2420683

2420684

2420688

2420690

2420691

2420692

2420693

2420694

2420695

2420696

2420697

2420698

2420700

2420701

2420702

2420703

2420704

2420705

2420706

2420707

2420711

242308_PM_at

242308_at

55283

56820_at

78010_at

7917304

A_23_P12241

A_33_P3238335

GE82340

GO:0000421

GO:0005215

GO:0005253

GO:0005261

GO:0005262

GO:0005267

GO:0005272

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005886

GO:0007626

GO:0008289

GO:0016020

GO:0019722

GO:0030154

GO:0031410

GO:0031901

GO:0031902

GO:0034220

GO:0035725

GO:0042491

GO:0043226

GO:0055085

GO:0070588

GO:0071805

GO:0072345

GO:0098655

GO:0098656

HMNXSV003013337

HMNXSV003053175

Hs.131450.0.A1_3p_at

Hs.49344.1.A1_3p_at

Hs.49344.1.A1_3p_x_at

Hs2.277871.1.S1_3p_s_at

ILMN_1775962

ILMN_2046611

PH_hs_0003437

PH_hs_0037637

TC01002825.hg

TC01005594.hg

g8922819_3p_at

Participates

as a member of

TRPs [plasma membrane] (Homo sapiens)

Inferred To

cup-5 [plasma membrane] (Caenorhabditis elegans)

Mcoln3 [plasma membrane] (Mus musculus)

Mcoln3 [plasma membrane] (Rattus norvegicus)

MCOLN3 [plasma membrane] (Bos taurus)

MCOLN3 [plasma membrane] (Canis familiaris)

MCOLN3 [plasma membrane] (Dictyostelium discoideum)

MCOLN3 [plasma membrane] (Gallus gallus)

MCOLN3 [plasma membrane] (Sus scrofa)

Trpml [plasma membrane] (Drosophila melanogaster)

Cross References

Guide to Pharmacology - Targets

503

ENSEMBL

ENSP00000359621, ENSG00000055732, ENSP00000342698, ENST00000341115, ENST00000370589

OpenTargets

ENSG00000055732

GeneCards

MCOLN3

HPA

ENSG00000055732-MCOLN3

PRO

Q8TDD5

Pharos - Targets

Q8TDD5

PDB

6AYF, 6AYE, 6AYG

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99758 ABCA3	11	ABCA3 [lamellar body membrane] (R-HSA-1369005) ABCA3 T1114M [lamellar body membrane] (R-HSA-5688390) ABCA3 N568D [lamellar body membrane] (R-HSA-5688388) ABCA3 E690K [lamellar body membrane] (R-HSA-5688389) ABCA3 E292V [lamellar body membrane] (R-HSA-5688394) ABCA3 L1553P [lamellar body membrane] (R-HSA-5683671) ABCA3 L326P [lamellar body membrane] (R-HSA-5683666) ABCA3 D253H [lamellar body membrane] (R-HSA-5683697) ABCA3 L101P [lamellar body membrane] (R-HSA-5683658) ABCA3 W1142* [lamellar body membrane] (R-HSA-5683691) ABCA3 T1173R [lamellar body membrane] (R-HSA-5683705)	0.527	2
UniProt:Q8WVC6 DCAKD	1	DCAKD [mitochondrial outer membrane] (R-HSA-9837353)	0.527	2
UniProt:Q8WZA1 POMGNT1	6	POMGNT1 [Golgi membrane] (R-HSA-5617040) POMGNT1 S550N [Golgi membrane] (R-HSA-5617094) POMGNT1 R605Vfs29 [Golgi membrane] (R-HSA-5617081) POMGNT1 R63 [Golgi membrane] (R-HSA-5617033) POMGNT1 W475* [Golgi membrane] (R-HSA-5617097) POMGNT1 P493R [Golgi membrane] (R-HSA-5617048)	0.527	2
UniProt:Q9GZU1 MCOLN1	2	MCOLN1 [plasma membrane] (R-HSA-3211764) MCOLN1 [endosome membrane] (R-HSA-917803)	0.527	3
UniProt:Q86XT9 TMEM219	1	TMEM219 [plasma membrane] (R-HSA-6800018)	0.527	2

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