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A1CF [nucleoplasm]
Stable Identifier
R-HSA-3211440
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
APOBEC1 complementation factor, A1CF_HUMAN, ACF
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
mRNA Editing (Homo sapiens)
mRNA Editing: C to U Conversion (Homo sapiens)
C4 deamination of cytidine (Homo sapiens)
C to U edited ApoB RNA:Editosome complex [nucleoplasm] (Homo sapiens)
A1CF [nucleoplasm] (Homo sapiens)
Editosome for C to U editing [nucleoplasm] (Homo sapiens)
Stem-looped mRNA:ACF complex [nucleoplasm] (Homo sapiens)
A1CF [nucleoplasm] (Homo sapiens)
Formation of the Editosome (Homo sapiens)
Binding of A1CF to stem-looped RNA (Homo sapiens)
A1CF [nucleoplasm] (Homo sapiens)
Stem-looped mRNA:ACF complex [nucleoplasm] (Homo sapiens)
A1CF [nucleoplasm] (Homo sapiens)
Binding of APOBEC-1 to form editosome (Homo sapiens)
Editosome for C to U editing [nucleoplasm] (Homo sapiens)
Stem-looped mRNA:ACF complex [nucleoplasm] (Homo sapiens)
A1CF [nucleoplasm] (Homo sapiens)
Stem-looped mRNA:ACF complex [nucleoplasm] (Homo sapiens)
A1CF [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NQ94 A1CF
Gene Names
A1CF, ACF, ASP
Chain
chain:1-594
Reference Genes
BioGPS Gene:29974 A1CF
COSMIC (genes):A1CF A1CF
CTD Gene:29974 A1CF
dbSNP Gene:29974 A1CF
ENSEMBL:ENSG00000148584 A1CF
ENSEMBL_homo_sapiens_GENE:ENSG00000148584.16 A1CF
HGNC:24086 A1CF
KEGG Gene (Homo sapiens):29974 A1CF
Monarch:29974 A1CF
NCBI Gene:29974 A1CF
OMIM:618199 A1CF
UCSC:Q9NQ94 A1CF
Reference Transcript
RefSeq:NM_001198818.1 A1CF
RefSeq:NM_001198820.1 A1CF
RefSeq:NM_138932.2 A1CF
RefSeq:NM_001198819.1 A1CF
RefSeq:XM_005269718.2 A1CF
RefSeq:XM_017016160.1 A1CF
RefSeq:NM_014576.3 A1CF
RefSeq:NM_138933.2 A1CF
RefSeq:XM_005269720.3 A1CF
Other Identifiers
11745515_a_at
11746909_a_at
16714348
220951_PM_s_at
220951_s_at
241547_PM_at
241547_at
29974
3289441
3289442
3289444
3289446
3289447
3289448
3289449
3289452
3289453
3289455
3289458
3289461
3289463
3289464
3289465
3289468
3289469
3289471
3289472
3289473
3289474
3289475
3289479
3289480
3289481
3289482
3289485
47095_at
57966_at
66976_r_at
7933640
A_23_P104224
A_24_P570378
GE55443
GO:0003676
GO:0003723
GO:0003727
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0006397
GO:0007566
GO:0010609
GO:0016071
GO:0016554
GO:0016556
GO:0022414
GO:0030895
GO:0043226
GO:0045293
GO:0048856
GO:0050821
GO:0060090
GO:0140767
GO:1901537
GO:2000623
HMNXSV003034468
Hs.268821.0.A1_3p_at
ILMN_1779670
ILMN_1806310
ILMN_1883785
ILMN_1893846
ILMN_2383229
PH_hs_0000888
PH_hs_0013769
TC10001292.hg
TC10002643.hg
g7656852_3p_a_at
Participates
as an input of
Binding of A1CF to stem-looped RNA (Homo sapiens)
as a component of
C to U edited ApoB RNA:Editosome complex [nucleoplasm] (Homo sapiens)
Stem-looped mRNA:ACF complex [nucleoplasm] (Homo sapiens)
Inferred To
a1cf [nucleoplasm]
(Xenopus tropicalis)
A1CF [nucleoplasm]
(Bos taurus)
A1CF [nucleoplasm]
(Canis familiaris)
A1CF [nucleoplasm]
(Gallus gallus)
A1CF [nucleoplasm]
(Sus scrofa)
A1cf [nucleoplasm]
(Mus musculus)
A1cf [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_055391.2
,
NP_620311.1
,
NP_001185748.1
,
NP_620310.1
,
XP_005269777.1
,
XP_016871649.1
,
NP_001185749.1
,
XP_005269775.1
,
NP_001185747.1
OpenTargets
ENSG00000148584
GeneCards
Q9NQ94
HPA
ENSG00000148584-A1CF
Ensembl
ENSG00000148584
,
ENST00000374001
,
ENST00000414883
,
ENSP00000363113
,
ENST00000373997
,
ENSP00000363105
,
ENST00000373993
,
ENST00000373995
,
ENSP00000363109
,
ENSP00000363107
,
ENST00000395495
,
ENSP00000397953
,
ENSP00000378873
PRO
Q9NQ94
Pharos - Targets
Q9NQ94
PDB
2CPD
HMDB Protein
HMDBP10774
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.718
6
UniProt:O76011 KRT34
1
KRT34 [cytosol]
(R-HSA-6809608)
0.556
3
UniProt:Q58EX7 PLEKHG4
1
PLEKHG4 [cytosol]
(R-HSA-9679579)
0.556
3
UniProt:Q04864 REL
2
REL [cytosol]
(R-HSA-1168579)
REL [nucleoplasm]
(R-HSA-1168585)
0.556
3
UniProt:Q7L591-3 DOK3
0.556
3
UniProt:Q9UFD9 RIM3A
0.556
3
UniProt:Q8NCR6 SMIP6
0.556
3
UniProt:Q7Z3K3 POGZ
0.556
3
UniProt:Q16082 HSPB2
0.556
3
UniProt:Q8N6F8 MET27
0.556
3
UniProt:Q04637-9 EIF4G1
0.556
3
UniProt:Q5BKX5-3 ACTMAP
0.556
3
UniProt:Q96G42 KLD7B
0.556
3
UniProt:O43482 OIP5
1
OIP5 [nucleoplasm]
(R-HSA-606286)
0.556
3
UniProt:Q15323 KRT31
1
KRT31 [cytosol]
(R-HSA-6809616)
0.556
3
UniProt:A8MQ03 CRTP1
0.556
3
UniProt:Q16610 ECM1
2
ECM1 [extracellular region]
(R-HSA-8848909)
ECM1 [platelet dense granule lumen]
(R-HSA-8848880)
0.556
3
UniProt:Q13643 FHL3
0.556
3
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.556
3
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