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p-S139-TCF3 [nucleoplasm]
Stable Identifier
R-HSA-3209894
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transcription factor E2-alpha, TFE2_HUMAN, TCF3
Locations in the PathwayBrowser for interactor UniProt:Q9Y4C2 TCAF1
Expand all
Developmental Biology (Homo sapiens)
Myogenesis (Homo sapiens)
Phosphorylation of E proteins by p38 MAPK (Homo sapiens)
p-S139-TCF3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15923 TCF3
Gene Names
TCF3, BHLHB21, E2A, ITF1
Chain
chain:1-654
Reference Genes
BioGPS Gene:6929 TCF3
COSMIC (genes):TCF3 TCF3
CTD Gene:6929 TCF3
dbSNP Gene:6929 TCF3
ENSEMBL:ENSG00000071564 TCF3
ENSEMBL_homo_sapiens_GENE:ENSG00000071564.19 TCF3
HGNC:11633 TCF3
KEGG Gene (Homo sapiens):6929 TCF3
Monarch:6929 TCF3
NCBI Gene:6929 TCF3
OMIM:147141 TCF3
UCSC:P15923 TCF3
Reference Transcript
RefSeq:XM_017027181.1 TCF3
RefSeq:NM_001136139.2 TCF3
RefSeq:XM_017027180.1 TCF3
RefSeq:XM_017027182.1 TCF3
RefSeq:NM_003200.3 TCF3
Other Identifiers
11717959_a_at
11745937_a_at
11755059_s_at
11755060_x_at
1373_at
1374_g_at
16866724
209151_PM_x_at
209151_x_at
209152_PM_s_at
209152_s_at
209153_PM_s_at
209153_s_at
210776_PM_x_at
210776_x_at
213730_PM_x_at
213730_x_at
213811_PM_x_at
213811_x_at
215260_PM_s_at
215260_s_at
3161002
3161003
32874_at
3845366
3845367
3845368
3845369
3845370
3845371
3845372
3845373
3845375
3845379
3845380
3845381
3845383
3845385
3845386
3845387
3845388
3845389
3845390
3845391
3845392
3845393
3845394
3845395
3845397
3845401
3845403
3845412
3845414
3845415
3845419
3845420
6929
8032290
A_23_P67708
A_24_P365365
GE57923
GE79922
GO:0000122
GO:0000278
GO:0000785
GO:0000791
GO:0000976
GO:0000978
GO:0000981
GO:0000987
GO:0001227
GO:0001228
GO:0002326
GO:0002376
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0006310
GO:0006351
GO:0006355
GO:0006357
GO:0007399
GO:0030154
GO:0030183
GO:0030890
GO:0031435
GO:0032991
GO:0033152
GO:0042803
GO:0043226
GO:0043425
GO:0045666
GO:0045787
GO:0045893
GO:0045944
GO:0046982
GO:0046983
GO:0048856
GO:0051091
GO:0061629
GO:0070644
GO:0070888
GO:0090575
GO:0140110
GO:0140297
GO:2000045
HMNXSV003018698
HMNXSV003056518
Hs.101047.1.S1_3p_s_at
Hs.101047.1.S2_3p_a_at
Hs.101047.4.S1_3p_a_at
Hs.101047.5.S1_3p_a_at
M31523_at
M65214_s_at
PH_hs_0024178
TC19001011.hg
TC19002285.hg
g339477_3p_a_at
Participates
as an output of
Phosphorylation of E proteins by p38 MAPK (Homo sapiens)
as a member of
phospho-E proteins [nucleoplasm] (Homo sapiens)
Other forms of this molecule
TCF3 [nucleoplasm]
Inferred To
phospho-hlh-2 [nucleoplasm]
(Caenorhabditis elegans)
phospho-tcf3b [nucleoplasm]
(Danio rerio)
phospho-Tcf3 [nucleoplasm]
(Mus musculus)
phospho-Tcf3 [nucleoplasm]
(Rattus norvegicus)
phospho-p-S139-TCF3 [nucleoplasm]
(Gallus gallus)
phospho-TCF3 [nucleoplasm]
(Bos taurus)
phospho-TCF3 [nucleoplasm]
(Canis familiaris)
phospho-TCF3 [nucleoplasm]
(Sus scrofa)
phospho-da [nucleoplasm]
(Drosophila melanogaster)
Modified Residues
Name
O-phospho-L-serine (unknown) at 139
Coordinate
139
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001129611.1
,
XP_016882670.1
,
XP_016882669.1
,
NP_003191.1
,
XP_016882671.1
OpenTargets
ENSG00000071564
HPA
ENSG00000071564-TCF3
GeneCards
P15923
Ensembl
ENST00000262965
,
ENSG00000071564
,
ENST00000588136
,
ENST00000395423
,
ENSP00000262965
,
ENSP00000468487
,
ENSP00000378813
PRO
P15923
Pharos - Targets
P15923
Orphanet
17918
PDB
2YPA
,
2YPB
,
3U5V
,
2MH0
,
6MGN
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17542 TAL1
1
TAL1 [nucleoplasm]
(R-HSA-8956511)
0.876
10
UniProt:P50553 ASCL1
1
ASCL1 [nucleoplasm]
(R-HSA-212402)
0.632
4
UniProt:Q02363 ID2
1
ID2 [nucleoplasm]
(R-HSA-452391)
0.564
2
UniProt:Q9Y4C2 TCAF1
0.556
3
UniProt:Q02535 ID3
1
ID3 [nucleoplasm]
(R-HSA-9613379)
0.556
3
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