Reactome | CD8B [early endosome membrane]

CD8B [early endosome membrane]

Stable Identifier

R-HSA-3149571

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

early endosome membrane

Synonyms

T-cell surface glycoprotein CD8 beta chain, CD8B_HUMAN

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - HIV Infection (Homo sapiens)
      - Host Interactions of HIV factors (Homo sapiens)
        
        The role of Nef in HIV-1 replication and disease pathogenesis (Homo sapiens)
        
        Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters (Homo sapiens)
        
        Nef Mediated CD8 Down-regulation (Homo sapiens)
        
        Degradation of CD8 (Homo sapiens)
        
        Internalized CD8:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)
        
        CD8B [early endosome membrane] (Homo sapiens)
        
        Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)
        
        Internalized CD8:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)
        
        CD8B [early endosome membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P10966 CD8B

Gene Names

CD8B, CD8B1

Chain

signal peptide:1-21, chain:22-210

Reference Genes

BioGPS Gene:926 CD8B

COSMIC (genes):CD8B CD8B

CTD Gene:926 CD8B

dbSNP Gene:926 CD8B

ENSEMBL:ENSG00000172116 CD8B

HGNC:1707 CD8B

KEGG:hsa:926 CD8B

Monarch:926 CD8B

NCBI Gene:926 CD8B

OMIM:186730 CD8B

UCSC:P10966 CD8B

Reference Transcript

Other Identifiers

11735474_a_at

11740654_a_at

11760737_at

16899943

17122276

17122594

207979_PM_s_at

207979_s_at

215332_PM_s_at

215332_s_at

2498444

2498448

2498450

2498454

2498456

2498457

2498458

2498459

2498460

2498461

2498462

2498463

2498464

2498465

2562966

2562967

2562968

2562969

2562970

2562974

2562978

2562979

2562980

2562981

2562982

2562983

2562984

2562985

2562987

2562988

2562989

2562992

2562993

2562994

2562999

2563000

39239_at

68800_at

8044154

8053594

926

A_21_P0012018

A_23_P159335

A_23_P357881

GE486118

GE81458

GO:0002250

GO:0002376

GO:0005515

GO:0005576

GO:0005886

GO:0006955

GO:0007169

GO:0009986

GO:0015026

GO:0016020

GO:0031901

GO:0042101

GO:0042110

GO:0042288

GO:0043235

GO:0050776

GO:0050852

GO:0060089

HMNXSV003008655

HMNXSV003010005

HMNXSV003025397

HMNXSV003029375

Hs.2299.4.S1_3p_a_at

ILMN_1669005

ILMN_1748601

ILMN_2354191

PH_hs_0030044

PH_hs_0033136

TC02000653.hg

TC02002060.hg

X13444_at

g4826666_3p_a_at

Participates

as a component of

Internalized CD8:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)

Other forms of this molecule

CD8B [plasma membrane]

Cross References

ENSEMBL

ENSP00000331172, ENST00000393761, ENSP00000340592, ENSP00000377356, ENST00000331469, ENST00000390655, ENST00000393759, ENSP00000377358, ENSP00000375070, ENST00000349455

OpenTargets

ENSG00000172116

HPA

ENSG00000172116-CD8B

PRO

P10966

Pharos - Targets

P10966

GlyGen

P10966

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