DDX41:DDX41 ligand [cytosol]

Stable Identifier
R-HSA-3134844
Type
Complex
Species
Homo sapiens
Related Species
Vaccinia virus, Human herpesvirus 1
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23142775 The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

Parvatiyar, K, Zhang, Z, Teles, RM, Ouyang, S, Jiang, Y, Iyer, SS, Zaver, SA, Schenk, M, Zeng, S, Zhong, W, Liu, ZJ, Modlin, RL, Liu, YJ, Cheng, G

Nat. Immunol. 2012
21892174 The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

Zhang, Z, Yuan, B, Bao, M, Lu, N, Kim, T, Liu, YJ

Nat. Immunol. 2011
Participants
components
Participant Of
output
This entity regulates
Positively
Disease
Name Identifier Synonyms
viral infectious disease 934 arbovirus infectious disease, Viral disease, Viral infection NOS, Viral infection, unspecified (disorder), Viral infection NOS, Viral disease (disorder), Viral disease, Viral infection NOS (disorder), Viral Infection, virus infection, virus infection, Viral: [infection NOS] or [illness]