K63polyUb-STING [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-3134805
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
MITA, TMEM173, ERIS
K63polyUb-STING [endoplasmic reticulum membrane] icon
Locations in the PathwayBrowser for interactor UniProt:O15260 SURF4
External Reference Information
External Reference
Gene Names
TMEM173, ERIS, MITA, STING
Chain
chain:1-379
Reference Transcript
Other Identifiers
0001410398
11727044_a_at
17000650
224916_at
224929_at
2877991
2877992
2877993
2877994
2877995
2877998
2878000
2878002
2878003
2878005
2878007
2878008
340061
38116
38534
4EF4
4EF5
4EMT
4EMU
4F5D
4F5E
4F5W
4F5Y
4F9E
4F9G
4KSY
4LOH
4LOI
4QXO
4QXP
4QXQ
4QXR
5BQX
5JEJ
65817_at
8114536
A_23_P61371
AAH47779
AC138517
ACI46648
AK290661
BAF83350
BC047779
CCDS4215
ENSG00000184584
ENSP00000331288
ENST00000330794
ENST00000330794.8
EntrezGene:340061
FJ222241
GE88570
GO:0000166
GO:0002218
GO:0002230
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005737
GO:0005739
GO:0005741
GO:0005783
GO:0005789
GO:0005886
GO:0006810
GO:0006915
GO:0006950
GO:0007165
GO:0008134
GO:0008150
GO:0008219
GO:0016020
GO:0016021
GO:0016032
GO:0016192
GO:0019899
GO:0019901
GO:0030659
GO:0030667
GO:0032092
GO:0032479
GO:0032481
GO:0032608
GO:0035438
GO:0039528
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0043312
GO:0044403
GO:0045087
GO:0045944
GO:0048471
GO:0051091
GO:0051607
GO:0061507
GO:0071360
GO:0071407
HGNC:27962
HPA038116
HPA038534
Hs.86347.1.A1_3p_at
Hs.86347.1.A2_3p_at
ILMN_1761447
ILMN_2145116
IPR029158
IPR033952
IPR038623
MIM:612374
MIM:615934
NM_198282
NP_938023
PF15009
PH_hs_0033001
TC05001845.hg
TMEM173
TMEM173-201
UPI000000DC5E
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 150
Coordinate
150
Modification
K63polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
Interactors (26)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q86WV6 TMEM173  5 0.933 12
 UniProt:Q9UHD2 TBK1  6 0.862 8
 UniProt:Q7Z434-1 MAVS      0.78 7
 UniProt:Q7Z434 MAVS  2 0.71 7
 UniProt:P42226 STAT6  6 0.631 12
 UniProt:O15260 SURF4  5 0.623 3
 ChEBI:75947 CG(2'5')      0.558 2
 ChEBI:75948 CG(2'5')      0.558 2
 UniProt:P09913 IFIT2  1 0.558 3
 UniProt:P09914 IFIT1  1 0.558 3
 UniProt:P27958-PRO_0000037575      0.543 5
 UniProt:Q16666 IFI16  1 0.524 2
 UniProt:O95786-1 DDX58      0.524 2
 UniProt:P46977 STT3A  1 0.499 2
 UniProt:P39656 DDOST  3 0.499 2
 UniProt:P51617 IRAK1  14 0.499 2
 UniProt:Q96N66 MBOAT7  1 0.499 2
 UniProt:O94822 LTN1  1 0.499 2
 UniProt:Q96A33 CCD47      0.499 2
 UniProt:O95470 SGPL1  1 0.499 2
 UniProt:Q96HR9-2 REEP6      0.488 2
 UniProt:Q9Y342 PLLP      0.488 2
 UniProt:O95214 LERL1      0.488 2
 UniProt:Q13190 STX5  5 0.488 2
 UniProt:P43308 SSR2  1 0.482 4
 UniProt:Q99IB8-PRO_0000045601      0.463 5