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PCSK6 [Golgi lumen]
Stable Identifier
R-HSA-3009047
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Proprotein convertase subtilisin/kexin type 6 ecNumber3.4.21.-/ecNumber, PCSK6_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Expression and Processing of Neurotrophins (Homo sapiens)
NGF processing (Homo sapiens)
Part of pro-beta-NGF is processed to mature beta-NGF (Homo sapiens)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Homo sapiens)
Subtilisin/kexin-like convertase [Golgi lumen] (Homo sapiens)
PCSK6 [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P29122 PCSK6
Gene Names
PCSK6, PACE4
Chain
signal peptide:1-63, propeptide:64-149, chain:150-969
Reference Genes
BioGPS Gene:5046 PCSK6
COSMIC (genes):PCSK6 PCSK6
CTD Gene:5046 PCSK6
dbSNP Gene:5046 PCSK6
ENSEMBL:ENSG00000140479 PCSK6
HGNC:8569 PCSK6
KEGG:hsa:5046 PCSK6
Monarch:5046 PCSK6
NCBI Gene:5046 PCSK6
OMIM:167405 PCSK6
UCSC:P29122 PCSK6
Reference Transcript
RefSeq:NM_001291309.1 PCSK6
RefSeq:NM_138323.2 PCSK6
RefSeq:NM_002570.4 PCSK6
RefSeq:NM_138324.2 PCSK6
RefSeq:NM_138322.3 PCSK6
RefSeq:NM_138319.3 PCSK6
RefSeq:NM_138325.3 PCSK6
Other Identifiers
11723385_s_at
11734526_a_at
11738236_a_at
11738631_a_at
11742242_at
11748165_a_at
11761162_at
1553531_PM_at
1553531_at
207414_PM_s_at
207414_s_at
210553_PM_x_at
210553_x_at
211262_PM_at
211262_at
211263_PM_s_at
211263_s_at
32001_s_at
3642176
3642177
3642178
3642179
3642180
3642181
3642182
3642190
3642191
3642192
3642193
3642194
3642195
3642197
3642199
3642201
3642203
3642204
3642205
3642206
3642207
3642208
3642209
3642211
3642212
3642213
3642214
3642219
3642220
3642221
3642224
3642230
3642232
3642233
3642234
3642235
3642238
3642239
3642241
3642242
3642243
3642244
3642245
3642246
3642255
3642256
3642257
3642258
3642259
3642263
3642269
3642270
3642271
3642272
3642281
3642285
3642290
3642300
3642302
3642303
3642304
3642307
3642314
3642315
3642320
3642321
3642322
3642323
3642324
3642326
3642328
5046
7991602
84775_at
90658_s_at
90660_at
ADDON002376.hg
A_21_P0014797
A_23_P151907
A_23_P390006
A_24_P189997
GE517227
GE59711
GE62904
GO:0003824
GO:0004175
GO:0004252
GO:0005515
GO:0005576
GO:0005615
GO:0005783
GO:0005796
GO:0005886
GO:0006508
GO:0007354
GO:0007368
GO:0008201
GO:0008233
GO:0008236
GO:0009100
GO:0009986
GO:0012505
GO:0016020
GO:0016485
GO:0016486
GO:0016787
GO:0030312
GO:0030510
GO:0031012
GO:0032902
GO:0032940
GO:0034369
GO:0043226
GO:0048406
GO:0051604
GO:0062023
GO:0140096
GO:1901135
HMNXSV003010216
HMNXSV003030033
HMNXSV003041825
HMNXSV003054015
Hs2.170414.8.S1_3p_at
Hs2.170414.8.S1_3p_x_at
ILMN_1676384
ILMN_1676595
ILMN_1710070
ILMN_1768577
ILMN_1802550
ILMN_2292592
M80482_at
PH_hs_0022325
TC15002009.hg
g2330550_3p_a_at
g4505576_3p_a_at
g666010_3p_at
g666012_3p_a_at
g666012_3p_x_at
p25017
p25946
Participates
as a member of
Subtilisin/kexin-like convertase [Golgi lumen] (Homo sapiens)
Other forms of this molecule
PCSK6 [extracellular region]
PCSK6 [extracellular region]
PCSK6 [plasma membrane]
Inferred To
PCSK6 [Golgi lumen]
(Bos taurus)
PCSK6 [Golgi lumen]
(Canis familiaris)
PCSK6 [Golgi lumen]
(Gallus gallus)
PCSK6 [Golgi lumen]
(Sus scrofa)
Pcsk6 [Golgi lumen]
(Mus musculus)
Pcsk6 [Golgi lumen]
(Rattus norvegicus)
Cross References
RefSeq
NP_612192.1
,
NP_612195.1
,
NP_612196.1
,
NP_001278238.1
,
NP_002561.1
,
NP_612197.1
,
NP_612198.2
Guide to Pharmacology - Targets
2386
OpenTargets
ENSG00000140479
ENSEMBL
ENST00000615296
,
ENST00000611967
,
ENSP00000479496
,
ENSP00000477768
,
ENST00000618548
,
ENSP00000478081
,
ENSP00000482760
,
ENST00000611716
ZINC - Substances
PCSK6_HUMAN
HPA
ENSG00000140479-PCSK6
ZINC target
P29122
PRO
P29122
Pharos - Targets
P29122
ZINC - Predictions - Purchasable
PCSK6_HUMAN
HMDB Protein
HMDBP01820
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC8 8
2
8 [extracellular region]
(R-COV-9755410)
8 [endoplasmic reticulum lumen]
(R-COV-9727283)
0.527
2
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