Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PPP2R3B [nucleoplasm]
Stable Identifier
R-HSA-3008955
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta, P2R3B_HUMAN, PR70, PR48, PPP2R3L, PP2A subunit B isoform PR48
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
Dephosphorylation of p107 (RBL1) by PP2A (Homo sapiens)
PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
Dephosphorylation of p130 (RBL2) by PP2A (Homo sapiens)
PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
E2F mediated regulation of DNA replication (Homo sapiens)
Inhibition of replication initiation of damaged DNA by RB1/E2F1 (Homo sapiens)
PP2A mediated localization of RB1 protein in chromatin (Homo sapiens)
PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)
PP2A demethylation by PPME1 (Homo sapiens)
MeL-PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
PP2A methylation by LCMT1 (Homo sapiens)
MeL-PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
PP2A [nucleoplasm] (Homo sapiens)
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
PPP2R3B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y5P8 PPP2R3B
Gene Names
PPP2R3B, PPP2R3L
Chain
chain:1-575
Reference Genes
BioGPS Gene:28227 PPP2R3B
COSMIC (genes):PPP2R3B PPP2R3B
CTD Gene:28227 PPP2R3B
dbSNP Gene:28227 PPP2R3B
ENSEMBL:ENSG00000167393 PPP2R3B
HGNC:13417 PPP2R3B
KEGG:hsa:28227 PPP2R3B
Monarch:28227 PPP2R3B
NCBI Gene:28227 PPP2R3B
OMIM:300339 PPP2R3B
UCSC:Q9Y5P8 PPP2R3B
Reference Transcript
RefSeq:NM_013239.4 PPP2R3B
Other Identifiers
11724073_a_at
11762591_at
17116706
219264_3p_s_at
219264_PM_s_at
219264_s_at
28227
3997111
3997113
3997114
3997115
3997116
3997117
3997118
3997119
3997120
3997121
3997122
3997123
3997124
3997125
3997126
3997127
3997128
3997129
3997130
3997131
3997132
3997133
3997134
3997135
3997136
3997137
3997138
3997139
3997140
3997141
3997142
3997143
3997144
3997145
3997154
3997155
3997156
3997163
3997170
3997171
4032915
4032917
4032918
4032919
4032920
4032921
4032922
4032923
4032924
4032925
4032926
4032927
4032928
4032929
4032930
4032931
4032932
4032933
4032934
4032935
4032936
4032937
4032938
4032939
4032940
4032941
4032942
4032943
4032944
4032945
4032946
4032947
4032948
4032949
4032958
4032959
4032960
4032967
4032974
4032975
51166_f_at
71651_at
8171087
8176986
89606_i_at
89607_r_at
90020_at
GO:0000159
GO:0005509
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006470
GO:0019888
GO:0043226
GO:0046872
GO:0051726
GO:0098772
HMNXSV003002532
HMNXSV003020784
ILMN_1689720
ILMN_1712257
ILMN_1752032
PH_hs_0007041
TC0X000795.hg
TC0Y000112.hg
g7019500_3p_a_at
g7019500_3p_x_at
Participates
as a component of
PP2A [nucleoplasm] (Homo sapiens)
as a candidate of
PPP2R3B,PPP2R2A [nucleoplasm] (Homo sapiens)
Inferred To
PR72 [nucleoplasm]
(Drosophila melanogaster)
ppp2r3b [nucleoplasm]
(Danio rerio)
PPP2R3B [nucleoplasm]
(Caenorhabditis elegans)
PPP2R3B [nucleoplasm]
(Canis familiaris)
PPP2R3B [nucleoplasm]
(Dictyostelium discoideum)
PPP2R3B [nucleoplasm]
(Mus musculus)
PPP2R3B [nucleoplasm]
(Sus scrofa)
Ppp2r3b [nucleoplasm]
(Rattus norvegicus)
LOC100298789 [nucleoplasm]
(Bos taurus)
Cross References
RefSeq
NP_037371.2
ENSEMBL
ENST00000711115
,
ENST00000390665
,
ENSP00000375080
,
ENSG00000167393
,
ENSG00000292327
,
ENSP00000518592
OpenTargets
ENSG00000167393
GeneCards
PPP2R3B
HPA
ENSG00000167393-PPP2R3B
PRO
Q9Y5P8
Pharos - Targets
Q9Y5P8
HMDB Protein
HMDBP09425
PDB
4I5L
,
4MEW
,
4I5N
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P67775 PPP2CA
4
PPP2CA [cytosol]
(R-HSA-165971)
PPP2CA [nucleoplasm]
(R-HSA-165978)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
0.643
3
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.556
3
UniProt:Q9HC29 NOD2
1
NOD2 [cytosol]
(R-HSA-168411)
0.553
5
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text