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OBSCN [cytosol]
Stable Identifier
R-HSA-3008877
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Obscurin, OBSCN_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
OBSCN [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
OBSCN [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
OBSCN [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ GEFs activate RHOQ (Homo sapiens)
RHOQ GEFs [cytosol] (Homo sapiens)
OBSCN [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VST9 OBSCN
Gene Names
OBSCN, KIAA1556, KIAA1639
Chain
chain:1-7968
Reference Genes
BioGPS Gene:84033 OBSCN
COSMIC (genes):OBSCN OBSCN
CTD Gene:84033 OBSCN
dbSNP Gene:84033 OBSCN
ENSEMBL:ENSG00000154358 OBSCN
ENSEMBL_homo_sapiens_GENE:ENSG00000154358.23 OBSCN
HGNC:15719 OBSCN
KEGG Gene (Homo sapiens):84033 OBSCN
Monarch:84033 OBSCN
NCBI Gene:84033 OBSCN
OMIM:608616 OBSCN
UCSC:Q5VST9 OBSCN
Reference Transcript
RefSeq:NM_001098623.2 OBSCN
RefSeq:NM_052843.3 OBSCN
Other Identifiers
11731344_a_at
11734313_at
16678361
229854_PM_at
229854_at
233029_PM_at
233029_at
2383998
2384000
2384005
2384006
2384007
2384008
2384009
2384010
2384011
2384013
2384015
2384016
2384017
2384021
2384028
2384029
2384030
2384032
2384034
2384035
2384037
2384039
2384042
2384047
2384051
2384057
2384058
2384059
2384060
2384061
2384062
2384063
2384064
2384067
2384068
2384069
2384070
2384071
2384072
2384073
2384074
2384075
2384076
2384078
2384079
2384080
2384081
2384082
2384083
2384084
2384085
2384087
2384088
2384091
2384092
2384094
2384095
2384098
2384100
2384101
2384104
2384105
2384107
2384108
2384114
2384115
2384116
2384119
2384120
2384122
2384123
2384124
2384125
2384126
2384127
2384129
2384130
2384131
2384138
2384139
2384140
2384141
2384142
2384143
2384144
2384145
2384146
2384147
2384148
2384149
2384150
2384151
2384152
2384153
2384154
2384155
2384156
2384158
2384159
2384161
2384163
2384164
2384166
2384167
2384168
2384170
2384171
2384173
2384174
2384175
2384179
2384181
2384187
2384188
2384189
2384190
2384191
2384192
2384193
2384194
2384199
2384200
2384203
2384204
2384205
2384206
2384211
2384212
2384215
2384216
2384217
2384218
2384219
2384220
2384221
2384222
2384223
2384224
2384225
2384226
2384227
2384228
2384229
2384230
2384231
2384232
2384233
2384234
2384235
2384236
2384237
2384238
2384239
7910265
84033
89875_at
A_24_P119685
A_24_P273157
A_33_P3404546
GE87570
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005085
GO:0005198
GO:0005515
GO:0005516
GO:0005524
GO:0005546
GO:0005547
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0007010
GO:0008092
GO:0008289
GO:0008307
GO:0010314
GO:0016020
GO:0016301
GO:0016310
GO:0016604
GO:0016740
GO:0023052
GO:0030016
GO:0030018
GO:0030154
GO:0030506
GO:0031430
GO:0031432
GO:0032266
GO:0036211
GO:0036309
GO:0042383
GO:0043226
GO:0043229
GO:0043325
GO:0045214
GO:0046872
GO:0048856
GO:0051056
GO:0070273
GO:0098772
GO:0106310
GO:0140096
HMNXSV003016051
HMNXSV003032364
Hs.118837.0.A1_3p_at
Hs.118837.0.A1_3p_x_at
Hs.287383.0.S1_3p_at
ILMN_1749667
PH_hs_0014825
PH_hs_0025816
PH_hs_0041173
TC01001888.hg
Participates
as a member of
RHOA GEFs [cytosol] (Homo sapiens)
RHOQ GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
OBSCN [cytosol]
(Mus musculus)
Obscn [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_443075.3
,
NP_001092093.2
Guide to Pharmacology - Targets
2131
OpenTargets
ENSG00000154358
GeneCards
Q5VST9
HPA
ENSG00000154358-OBSCN
Ensembl
ENSP00000499633
,
ENST00000662438
,
ENSP00000489816
,
ENST00000284548
,
ENSP00000409493
,
ENST00000636476
,
ENST00000422127
,
ENSG00000154358
,
ENSP00000284548
PRO
Q5VST9
Pharos - Targets
Q5VST9
Orphanet
24776
HMDB Protein
HMDBP08785
PDB
5TZM
,
2EDL
,
6MG9
,
2N56
,
2CR6
,
2YZ8
,
4RSV
,
2EDQ
,
1V1C
,
4C4K
,
2EDH
,
2EDF
,
2DM7
,
2GQH
,
2MWC
,
7R67
,
2DKU
,
2EDT
,
2EO1
,
2EDR
,
2EDW
,
2E7B
,
2ENY
,
7R68
,
4UOW
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