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RHOT2 [mitochondrial outer membrane]
Stable Identifier
R-HSA-3006730
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Synonyms
Mitochondrial Rho GTPase 2, MIRO2_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
Rho GTPase cycle (Homo sapiens)
GAPs inactivate Rho GTPase:GTP by hydrolysis (Homo sapiens)
RhoGTPase:GDP [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
RhoGTPase:GTP [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
GDIs block activation of Rho GTPase:GDP (Homo sapiens)
RhoGTPase:GDP [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
GEFs activate Rho GTPase:GDP (Homo sapiens)
RhoGTPase:GDP [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
RhoGTPase:GTP [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
Rho GTPase:GTP activates downstream effectors (Homo sapiens)
RhoGTPase:GTP [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
RhoGTPase:GTP:Effectors complex [plasma membrane] (Homo sapiens)
Rho GTPases [plasma membrane] (Homo sapiens)
RHOT2 [mitochondrial outer membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IXI1 RHOT2
Gene Names
RHOT2, ARHT2, C16orf39
Chain
chain:1-618
Reference Genes
BioGPS Gene:89941 RHOT2
COSMIC (genes):RHOT2 RHOT2
CTD Gene:89941 RHOT2
dbSNP Gene:89941 RHOT2
ENSEMBL:ENSG00000140983 RHOT2
HGNC:21169 RHOT2
KEGG Gene (Homo sapiens):89941 RHOT2
Monarch:89941 RHOT2
NCBI Gene:89941 RHOT2
OMIM:613889 RHOT2
UCSC:Q8IXI1 RHOT2
Reference Transcript
RefSeq:NM_138769.2 RHOT2
Other Identifiers
0001980706
11737635_a_at
11744386_a_at
16814455
221789_3p_x_at
221789_x_at
222131_3p_x_at
222131_x_at
3643231
3643232
3643234
3643236
3643238
3643241
3643242
3643243
3643245
3643247
3643248
3643250
3643252
3643254
3643256
3643257
3643259
3643261
3643263
3643266
3643267
3643268
3643269
3643270
3643271
4890925_3p_x_at
65770_at
7991989
89941
A_23_P15067
A_33_P3393350
GE57005
GO:0000166
GO:0003674
GO:0003924
GO:0005509
GO:0005515
GO:0005525
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005829
GO:0005886
GO:0006810
GO:0007005
GO:0007165
GO:0008150
GO:0008219
GO:0010821
GO:0016020
GO:0016021
GO:0016787
GO:0019725
GO:0030705
GO:0031307
GO:0042592
GO:0043167
GO:0043226
GO:0046872
GO:0047497
GO:0051056
GO:0061024
GO:0097345
Hs.21497.0.S1_3p_s_at
Hs.21497.1.S1_3p_s_at
Hs.21497.1.S1_3p_x_at
ILMN_1669310
PH_hs_0025948
TC16000024.hg
Participant Of
hasMember
Rho GTPases [plasma membrane]
Other forms of this molecule
RHOT2 [cytosol]
Inferred To
miro-1 [mitochondrial outer membrane] (Caenorhabditis elegans)
rhot2 [mitochondrial outer membrane] (Danio rerio)
rhot2 [mitochondrial outer membrane] (Xenopus tropicalis)
GEM1 [mitochondrial outer membrane] (Saccharomyces cerevisiae)
RHOT2 [mitochondrial outer membrane] (Gallus gallus)
RHOT2 [mitochondrial outer membrane] (Sus scrofa)
Miro [mitochondrial outer membrane] (Drosophila melanogaster)
Rhot2 [mitochondrial outer membrane] (Mus musculus)
Rhot2 [mitochondrial outer membrane] (Rattus norvegicus)
gem1 [mitochondrial outer membrane] (Schizosaccharomyces pombe)
WDR90 [mitochondrial outer membrane] (Canis familiaris)
Cross References
RefSeq
NP_620124.1
OpenTargets
ENSG00000140983
GeneCards
Q8IXI1
HPA
ENSG00000140983-RHOT2
Ensembl
ENSG00000140983
,
ENST00000315082
,
ENSP00000321971
PRO
Q8IXI1
PDB
5KUT
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N661 TMEM86B
1
TMEM86B [endoplasmic reticulum membrane]
(R-HSA-8874443)
0.556
3
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