Reactome | RHOT2 [mitochondrial outer membrane]

RHOT2 [mitochondrial outer membrane]

Stable Identifier

R-HSA-3006730

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Mitochondrial Rho GTPase 2, MIRO2_HUMAN

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External Reference Information

External Reference

UniProt:Q8IXI1 RHOT2

Gene Names

RHOT2, ARHT2, C16orf39

Chain

chain:1-618

Reference Genes

BioGPS Gene:89941 RHOT2

COSMIC (genes):RHOT2 RHOT2

CTD Gene:89941 RHOT2

dbSNP Gene:89941 RHOT2

ENSEMBL:ENSG00000140983 RHOT2

ENSEMBL_homo_sapiens_GENE:ENSG00000140983.15 RHOT2

HGNC:21169 RHOT2

KEGG Gene (Homo sapiens):89941 RHOT2

Monarch:89941 RHOT2

NCBI Gene:89941 RHOT2

OMIM:613889 RHOT2

UCSC:Q8IXI1 RHOT2

Reference Transcript

RefSeq:NM_138769.2 RHOT2

Other Identifiers

11737635_a_at

11744386_a_at

16814455

221789_3p_x_at

221789_PM_x_at

221789_x_at

222131_3p_x_at

222131_PM_x_at

222131_x_at

3643231

3643232

3643234

3643236

3643238

3643241

3643242

3643243

3643245

3643247

3643248

3643250

3643252

3643254

3643256

3643257

3643259

3643261

3643263

3643266

3643267

3643268

3643269

3643270

3643271

4890925_3p_x_at

65770_PM_at

65770_at

7991989

89941

A_23_P15067

A_33_P3393350

GE57005

GO:0000166

GO:0003824

GO:0003924

GO:0005509

GO:0005515

GO:0005525

GO:0005739

GO:0005741

GO:0007005

GO:0007010

GO:0007015

GO:0007018

GO:0007165

GO:0007264

GO:0012501

GO:0016020

GO:0016787

GO:0019725

GO:0023052

GO:0043226

GO:0046872

GO:0047497

GO:0061024

GO:0097345

HMNXSV003031803

Hs.21497.0.S1_3p_s_at

Hs.21497.1.S1_3p_s_at

Hs.21497.1.S1_3p_x_at

ILMN_1669310

PH_hs_0025948

TC16000024.hg

Participates

as a component of

Inferred To

RHOT1 [mitochondrial outer membrane] (Caenorhabditis elegans)

RHOT1 [mitochondrial outer membrane] (Dictyostelium discoideum)

RHOT1 [mitochondrial outer membrane] (Drosophila melanogaster)

RHOT1 [mitochondrial outer membrane] (Saccharomyces cerevisiae)

RHOT1 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

RHOT2 [mitochondrial outer membrane] (Bos taurus)

RHOT2 [mitochondrial outer membrane] (Danio rerio)

RHOT2 [mitochondrial outer membrane] (Gallus gallus)

RHOT2 [mitochondrial outer membrane] (Mus musculus)

RHOT2 [mitochondrial outer membrane] (Rattus norvegicus)

RHOT2 [mitochondrial outer membrane] (Sus scrofa)

RHOT2 [mitochondrial outer membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_620124.1

OpenTargets

ENSG00000140983

HPA

ENSG00000140983-RHOT2

GeneCards

Q8IXI1

Ensembl

ENSP00000321971, ENSG00000140983, ENST00000315082

PRO

Q8IXI1

Pharos - Targets

Q8IXI1

PDB

5KUT

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	6

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