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HNF1A [nucleoplasm]
Stable Identifier
R-HSA-3004629
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Hepatocyte nuclear factor 1-alpha, HNF1A_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:Q9Y463 DYR1B
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in beta cells (Homo sapiens)
HNF1A-dependent synthesis of FOXA3 (Homo sapiens)
HNF1A [nucleoplasm] (Homo sapiens)
HNF1A-dependent synthesis of GLUT2 protein (Homo sapiens)
HNF1A [nucleoplasm] (Homo sapiens)
HNF1A-dependent synthesis of HNF4A (Homo sapiens)
HNF1A [nucleoplasm] (Homo sapiens)
HNF1A-dependent synthesis of HNF4G protein (Homo sapiens)
HNF1A [nucleoplasm] (Homo sapiens)
HNF1A-dependent synthesis of the L isoform of PKLR protein (Homo sapiens)
HNF1A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20823 HNF1A
Gene Names
HNF1A, TCF1
Chain
chain:1-631
Reference Genes
BioGPS Gene:6927 HNF1A
COSMIC (genes):HNF1A HNF1A
CTD Gene:6927 HNF1A
dbSNP Gene:6927 HNF1A
ENSEMBL:ENSG00000135100 HNF1A
ENSEMBL_homo_sapiens_GENE:ENSG00000135100.19 HNF1A
HGNC:11621 HNF1A
KEGG Gene (Homo sapiens):6927 HNF1A
Monarch:6927 HNF1A
NCBI Gene:6927 HNF1A
OMIM:142410 HNF1A
UCSC:P20823 HNF1A
Reference Transcript
RefSeq:NM_000545.6 HNF1A
RefSeq:NM_001306179.1 HNF1A
Other Identifiers
11734275_at
11734276_at
11752853_a_at
16758011
210515_PM_at
210515_at
216930_3p_at
216930_PM_at
216930_at
3434682
3434683
3434692
3434693
3434696
3434697
3434698
3434699
3434702
3434703
3434704
3434705
3434706
3434707
3434708
3434709
34639_at
34640_at
6927
7959234
A_14_P107948
A_23_P36757
A_24_P372913
A_33_P3299119
A_33_P3299122
A_33_P3328312
GE57986
GE80925
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001228
GO:0001889
GO:0003014
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005694
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0023052
GO:0030073
GO:0031016
GO:0032991
GO:0035623
GO:0042593
GO:0043226
GO:0045893
GO:0045944
GO:0046323
GO:0046983
GO:0048856
GO:0055085
GO:0060261
GO:0140110
HMNXSV003021509
HMNXSV003032075
Hs.73888.1.S1_3p_x_at
ILMN_1659929
M57732_at
PH_hs_0029907
TC12000952.hg
U73499_at
g184264_3p_at
This entity regulates
Positively
HNF1A-dependent synthesis of FOXA3
(Homo sapiens)
HNF1A-dependent synthesis of HNF4A
(Homo sapiens)
HNF1A-dependent synthesis of HNF4G protein
(Homo sapiens)
HNF1A-dependent synthesis of GLUT2 protein
(Homo sapiens)
HNF1A-dependent synthesis of the L isoform of PKLR protein
(Homo sapiens)
Cross References
RefSeq
NP_000536.5
,
NP_001293108.1
OpenTargets
ENSG00000135100
GeneCards
P20823
Ensembl
ENST00000538646
,
ENST00000540108
,
ENSP00000440361
,
ENSG00000135100
,
ENST00000541924
,
ENSP00000443964
,
ENSP00000445445
PRO
P20823
Pharos - Targets
P20823
Orphanet
17227
PDB
2GYP
,
1IC8
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H0N5 PHS2
0.763
5
UniProt:Q9Y463 DYR1B
0.71
4
UniProt:P61457 PCBD1
1
PCBD1 [cytosol]
(R-HSA-71131)
0.707
4
UniProt:P35680 HNF1B
1
HNF1B [nucleoplasm]
(R-HSA-3004721)
0.564
2
UniProt:Q92786 PROX1
0.524
3
UniProt:Q9UBS8 RNF14
1
RNF14 [cytosol]
(R-HSA-5688974)
0.482
2
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