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GRIA3 [plasma membrane]
Stable Identifier
R-HSA-3004508
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Glutamate receptor 3, GRIA3_HUMAN, GluR3
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
SALM2 associate with AMPA and NMDA receptors (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
SALM2:AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Unblocking of GRIN1:GRIN2 NMDA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
Activation of AMPA receptors (Homo sapiens)
Activation of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Activation of Ca permeable AMPA receptors (Homo sapiens)
Ca permeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptor ligand binding (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptor ligand binding (Homo sapiens)
Ca permeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Trafficking of AMPA receptors (Homo sapiens)
Trafficking of GluR1-containing AMPA receptors (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors (Homo sapiens)
Endocytosis of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptors (with phospho GluR2 S880) [plasma membrane] (Homo sapiens)
AMPA receptors (heteromers) with phopho GluR2 [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to synapse (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P42263 GRIA3
Gene Names
GRIA3, GLUR3, GLURC
Chain
signal peptide:1-28, chain:29-894
Reference Genes
BioGPS Gene:2892 GRIA3
COSMIC (genes):GRIA3 GRIA3
CTD Gene:2892 GRIA3
dbSNP Gene:2892 GRIA3
ENSEMBL:ENSG00000125675 GRIA3
HGNC:4573 GRIA3
KEGG Gene (Homo sapiens):2892 GRIA3
Monarch:2892 GRIA3
NCBI Gene:2892 GRIA3
OMIM:305915 GRIA3
UCSC:P42263 GRIA3
Reference Transcript
RefSeq:NM_000828.4 GRIA3
RefSeq:NM_007325.4 GRIA3
Other Identifiers
0006420017
11725753_a_at
11725754_at
11745051_a_at
11750139_a_at
1569290_s_at
17106688
206730_at
208032_s_at
230144_at
2749280
2892
35048_at
35049_g_at
3989449
3989450
3989451
3989455
3989486
3989501
3989509
3989520
3989521
3989523
3989527
3989528
3989530
3989534
3989539
3989553
3989557
3989573
3989576
3989577
3989580
3989581
3989582
3989583
3989584
3989585
3989586
42957_at
8169717
90951_at
A_14_P119045
A_14_P121798
A_14_P201729
A_24_P143127
A_32_P177897
GE60079
GE87957
GO:0001540
GO:0003674
GO:0004970
GO:0004971
GO:0005216
GO:0005575
GO:0005622
GO:0005737
GO:0005886
GO:0006810
GO:0006811
GO:0007165
GO:0007215
GO:0007267
GO:0007268
GO:0008150
GO:0015276
GO:0016020
GO:0016021
GO:0022857
GO:0030054
GO:0030666
GO:0031410
GO:0032281
GO:0032991
GO:0034220
GO:0035235
GO:0038023
GO:0043197
GO:0043226
GO:0045202
GO:0045211
GO:0055085
GO:0060078
GO:2000310
HMNXSV003028607
Hs.274461.0.A1_3p_at
ILMN_1782043
ILMN_2388669
PH_hs_0024278
TC0X000601.hg
X82068_at
g4504114_3p_a_at
g6598324_3p_at
Participates
as a member of
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
Other forms of this molecule
GRIA3 [endocytic vesicle membrane]
Inferred To
glr-4 [plasma membrane]
(Caenorhabditis elegans)
GluRIIA [plasma membrane]
(Drosophila melanogaster)
glr-1 [plasma membrane]
(Caenorhabditis elegans)
glr-7 [plasma membrane]
(Caenorhabditis elegans)
Ir21a [plasma membrane]
(Drosophila melanogaster)
Ir75d [plasma membrane]
(Drosophila melanogaster)
GluRIID [plasma membrane]
(Drosophila melanogaster)
Ir75a [plasma membrane]
(Drosophila melanogaster)
GluRIA [plasma membrane]
(Drosophila melanogaster)
GluRIIC [plasma membrane]
(Drosophila melanogaster)
gria3b [plasma membrane]
(Danio rerio)
glr-5 [plasma membrane]
(Caenorhabditis elegans)
GRIA3 [plasma membrane]
(Canis familiaris)
GRIA3 [plasma membrane]
(Gallus gallus)
GRIA3 [plasma membrane]
(Sus scrofa)
KaiR1D [plasma membrane]
(Drosophila melanogaster)
glr-2 [plasma membrane]
(Caenorhabditis elegans)
Ir75c [plasma membrane]
(Drosophila melanogaster)
Ir84a [plasma membrane]
(Drosophila melanogaster)
GluRIIE [plasma membrane]
(Drosophila melanogaster)
GluRIIB [plasma membrane]
(Drosophila melanogaster)
Gria3 [plasma membrane]
(Mus musculus)
Gria3 [plasma membrane]
(Rattus norvegicus)
Ir25a [plasma membrane]
(Drosophila melanogaster)
Homologues of GRIA3 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GRIA3 [plasma membrane]
(Drosophila melanogaster)
Ir64a [plasma membrane]
(Drosophila melanogaster)
glr-6 [plasma membrane]
(Caenorhabditis elegans)
glr-3 [plasma membrane]
(Caenorhabditis elegans)
GluRIB [plasma membrane]
(Drosophila melanogaster)
Ir93a [plasma membrane]
(Drosophila melanogaster)
Ir76b [plasma membrane]
(Drosophila melanogaster)
Ir8a [plasma membrane]
(Drosophila melanogaster)
clumsy [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_000819.3
,
NP_015564.4
Guide to Pharmacology - Targets
446
OpenTargets
ENSG00000125675
HPA
ENSG00000125675-GRIA3
GeneCards
P42263
Ensembl
ENSP00000478489
,
ENSG00000125675
,
ENST00000620443
,
ENST00000622768
,
ENSP00000481554
ZINC target
P42263
PRO
P42263
Pharos - Targets
P42263
Orphanet
16167
GlyGen
P42263
HMDB Protein
HMDBP12049
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