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FGD3 [cytosol]
Stable Identifier
R-HSA-3000205
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
FYVE, RhoGEF and PH domain-containing protein 3, FGD3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
FGD3 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
FGD3 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
FGD3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5JSP0 FGD3
Gene Names
FGD3, ZFYVE5
Chain
chain:1-725
Reference Genes
BioGPS Gene:89846 FGD3
COSMIC (genes):FGD3 FGD3
CTD Gene:89846 FGD3
dbSNP Gene:89846 FGD3
ENSEMBL:ENSG00000127084 FGD3
HGNC:16027 FGD3
KEGG:hsa:89846 FGD3
Monarch:89846 FGD3
NCBI Gene:89846 FGD3
OMIM:617554 FGD3
UCSC:Q5JSP0 FGD3
Reference Transcript
RefSeq:NM_001083536.1 FGD3
RefSeq:XM_017015274.1 FGD3
RefSeq:NM_033086.2 FGD3
RefSeq:NM_001286993.1 FGD3
Other Identifiers
11745742_s_at
11750360_s_at
1555407_PM_s_at
1555407_s_at
17086818
227811_PM_at
227811_at
3179552
3179553
3179555
3179556
3179557
3179558
3179559
3179560
3179561
3179562
3179563
3179564
3179565
3179567
3179569
3179571
3179572
3179573
3179574
3179575
3179576
3179577
3179578
3179581
3179584
3179588
3179590
3179591
3179592
3179593
3179594
3179595
3179596
3179597
3179598
3179599
3179600
3179601
3179629
3179631
3179633
3179635
3179636
51777_at
8156373
89846
A_14_P109820
A_14_P132348
A_23_P134980
A_24_P153840
GE55330
GO:0001726
GO:0005085
GO:0005737
GO:0005794
GO:0005829
GO:0005856
GO:0007010
GO:0008360
GO:0030027
GO:0030036
GO:0031267
GO:0043087
GO:0043226
GO:0046847
GO:0046872
GO:0051056
GO:0098772
HMNXSV003026437
HMNXSV003032917
Hs.5013.0.S1_3p_at
ILMN_1772686
PH_hs_0024857
TC09000440.hg
Participates
as a member of
CDC42 GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
exc-5 [cytosol]
(Caenorhabditis elegans)
Fgd3 [cytosol]
(Rattus norvegicus)
FGD3 [cytosol]
(Bos taurus)
FGD3 [cytosol]
(Canis familiaris)
FGD3 [cytosol]
(Gallus gallus)
FGD3 [cytosol]
(Mus musculus)
FGD3 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001273922.1
,
XP_016870763.1
,
NP_001077005.1
,
NP_149077.2
ENSEMBL
ENSP00000336914
,
ENSP00000364631
,
ENSP00000496819
,
ENST00000468206
,
ENSP00000413833
,
ENST00000375482
,
ENSP00000432310
,
ENST00000467786
,
ENST00000416701
,
ENST00000337352
OpenTargets
ENSG00000127084
HPA
ENSG00000127084-FGD3
PRO
Q5JSP0
Pharos - Targets
Q5JSP0
HMDB Protein
HMDBP08392
PDB
2COC
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