CUBN:AMN transports extracellular GIF:Cbl to endosome

Stable Identifier
R-HSA-3000137
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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The cubilin:protein amnionless (CUBN:AMN) complex mediates the internalisation and endocytosis of gastric internal factor:cobalamin (GIF:Cbl) into mucosal cells of the distal ileum (Fyfe et al. 2004).

Literature References
PubMed ID Title Journal Year
14576052 The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless

Fyfe, JC, Madsen, M, Højrup, P, Christensen, EI, Tanner, SM, de la Chapelle, A, He, Q, Moestrup, SK

Blood 2004
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created