SUMO2,3-BRCA1 [nucleoplasm]

Stable Identifier
R-HSA-2997624
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
SUMO2 N-glycyl-lys BRCA1, Breast cancer type 1 susceptibility protein ecNumber6.3.2.-/ecNumber, BRCA1_HUMAN
SUMO2,3-BRCA1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:P51587 BRCA2
Literature References
PubMed ID Title Journal Year
25218447 Uncovering global SUMOylation signaling networks in a site-specific manner

Hendriks, IA, D'Souza, RC, Yang, B, Verlaan-de Vries, M, Mann, M, Vertegaal, AC

Nat. Struct. Mol. Biol. 2014
External Reference Information
External Reference
Gene Names
BRCA1, RNF53
Chain
chain:1-1863
Other Identifiers
0000510746
11735584_x_at
11744317_x_at
11749632_a_at
11750373_a_at
11755416_x_at
16845349
1993_s_at
204531_s_at
211851_x_at
2395433
33724_at
3506844
3758316
3758318
3758319
3758321
3758323
3758324
3758334
3758335
3758337
3758341
3758342
3758344
3758345
3758350
3758351
3758355
3758357
3758358
3758359
3758360
3758361
3758362
3758363
3758364
3758366
3758367
3758368
3758371
3758372
3758374
3758375
604_at
672
69578_at
8015769
A_23_P207400
GE475511
GE59309
GO:0000151
GO:0000228
GO:0000278
GO:0000724
GO:0000729
GO:0000793
GO:0000794
GO:0000800
GO:0003674
GO:0003677
GO:0003684
GO:0003713
GO:0003723
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005815
GO:0005856
GO:0005886
GO:0006259
GO:0006260
GO:0006281
GO:0006301
GO:0006302
GO:0006303
GO:0006310
GO:0006349
GO:0006357
GO:0006359
GO:0006464
GO:0006629
GO:0006631
GO:0006633
GO:0006915
GO:0006950
GO:0006974
GO:0006978
GO:0007010
GO:0007049
GO:0007059
GO:0007098
GO:0007165
GO:0008092
GO:0008134
GO:0008150
GO:0008219
GO:0008270
GO:0008274
GO:0008283
GO:0008630
GO:0009048
GO:0009058
GO:0009790
GO:0010212
GO:0010575
GO:0010628
GO:0015631
GO:0016567
GO:0016579
GO:0016604
GO:0016740
GO:0019899
GO:0022607
GO:0030521
GO:0031398
GO:0031436
GO:0031625
GO:0032991
GO:0033147
GO:0034641
GO:0035066
GO:0035067
GO:0042127
GO:0042802
GO:0042981
GO:0043009
GO:0043167
GO:0043226
GO:0043627
GO:0044030
GO:0044212
GO:0044281
GO:0044818
GO:0045717
GO:0045739
GO:0045766
GO:0045892
GO:0045893
GO:0045944
GO:0046600
GO:0046872
GO:0048646
GO:0048856
GO:0050681
GO:0051276
GO:0051571
GO:0051572
GO:0051573
GO:0051574
GO:0051865
GO:0070063
GO:0070317
GO:0070512
GO:0070531
GO:0071158
GO:0071356
GO:0071681
GO:0072425
GO:0085020
GO:1901796
GO:1902042
GO:1990904
GO:2000378
GO:2000617
GO:2000620
ILMN_1738027
ILMN_2311089
L78833_cds1_at
PH_hs_0011459
TC17001553.hg
TC17002645.hg
U64805_s_at
g2218153_3p_a_at
g6552300_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at unknown position
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Interactors (45)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9BX63 BRIP1  2 0.976 28
 UniProt:Q99728 BARD1  2 0.948 16
 UniProt:Q86YC2 PALB2  1 0.909 27
 UniProt:Q99708 RBBP8  4 0.908 12
 UniProt:Q6UWZ7 ABRAXAS1  1 0.819 15
 UniProt:P03372 ESR1  8 0.811 16
 UniProt:O15360 FANCA  1 0.753 5
 UniProt:P51587 BRCA2  2 0.737 8
 UniProt:Q06609 RAD51  2 0.731 6
 UniProt:Q96RL1 UIMC1  1 0.722 10
 UniProt:Q14192 FHL2  1 0.715 6
 UniProt:P16104 H2AX  7 0.714 4
 UniProt:Q12888 TP53BP1  3 0.714 5
 UniProt:P27694 RPA1  2 0.669 3
 UniProt:Q14676 MDC1  6 0.648 4
 UniProt:P78347 GTF2I      0.61 5
 UniProt:Q8WX92 NELFB  3 0.602 5
 UniProt:Q6PJG6 BRAT1      0.602 6
 UniProt:P63165 SUMO1  155 0.602 3
 UniProt:Q9BXW9 FANCD2  3 0.602 3
 UniProt:Q61188 Ezh2  1 0.591 5
 UniProt:P61956 SUMO2  5 0.589 2
 UniProt:Q9GZX5 ZNF350  1 0.581 3
 UniProt:P62140 PPP1CB  4 0.581 3
 UniProt:P38398 BRCA1  5 0.564 2
 UniProt:Q16666 IFI16  1 0.556 9
 UniProt:P04637 TP53  27 0.544 2
 UniProt:P03126 VE6      0.544 7
 UniProt:P03129 VE7      0.544 5
 UniProt:Q92560 BAP1  1 0.543 3
 UniProt:Q9ULW0 TPX2  2 0.527 4
 UniProt:P40692 MLH1  3 0.527 2
 UniProt:P46736 BRCC3  2 0.527 2
 UniProt:Q13085 ACACA  2 0.524 2
 UniProt:P36873 PPP1CC  1 0.524 2
 UniProt:P62136 PPP1CA  1 0.524 2
 UniProt:Q6NZY4 ZCHC8      0.524 2
 UniProt:P11388 TOP2A  3 0.524 3
 UniProt:P10809 HSPD1  6 0.508 2
 UniProt:P52292 KPNA2  2 0.508 3
 UniProt:Q7Z569 BRAP  2 0.508 3
 UniProt:O75330 HMMR  2 0.499 4
 UniProt:P24385 CCND1  4 0.463 3
 UniProt:O14757 CHEK1  3 0.463 3
 UniProt:P10415 BCL2  1 0.463 6
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