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SMC5 [nucleoplasm]
Stable Identifier
R-HSA-2993751
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Structural maintenance of chromosomes protein 5, SMC5_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of DNA damage response and repair proteins (Homo sapiens)
SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Homo sapiens)
SMC5-SMC6 Complex [nucleoplasm] (Homo sapiens)
SMC5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IY18 SMC5
Gene Names
SMC5, KIAA0594, SMC5L1
Chain
chain:1-1101
Reference Genes
BioGPS Gene:23137 SMC5
COSMIC (genes):SMC5 SMC5
CTD Gene:23137 SMC5
dbSNP Gene:23137 SMC5
ENSEMBL:ENSG00000198887 SMC5
HGNC:20465 SMC5
Monarch:23137 SMC5
NCBI Gene:23137 SMC5
OMIM:609386 SMC5
UCSC:Q8IY18 SMC5
Reference Transcript
RefSeq:NM_015110.3 SMC5
Other Identifiers
11722517_a_at
11722518_a_at
11758523_s_at
17085779
212926_PM_at
212926_at
212927_3p_at
212927_PM_at
212927_at
23137
237725_PM_x_at
237725_x_at
3125341
3125344
3125346
3174225
3174226
3174227
3174228
3174229
3174230
3174231
3174232
3174233
3174234
3174236
3174237
3174238
3174240
3174242
3174244
3174245
3174246
3174247
3174250
3174251
3174252
3174257
3174258
3174259
3174260
3174262
3174263
3174264
3174266
3174267
3174268
3174269
3174270
3174271
3174294
41379_at
78866_at
8155770
A_14_P134191
A_23_P146526
A_23_P349615
A_32_P126609
GE53299
GO:0000217
GO:0000722
GO:0000724
GO:0000775
GO:0000781
GO:0000803
GO:0003677
GO:0003697
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0006281
GO:0006302
GO:0006310
GO:0006325
GO:0006974
GO:0007059
GO:0016605
GO:0016607
GO:0016787
GO:0016887
GO:0016925
GO:0019827
GO:0030054
GO:0030261
GO:0030915
GO:0032200
GO:0032204
GO:0034184
GO:0035061
GO:0035861
GO:0043226
GO:0044772
GO:0044828
GO:0051301
GO:0051984
GO:0071459
GO:0090398
GO:0140588
HMNXSV003020129
Hs.103283.0.A1_3p_at
Hs.103283.0.A2_3p_x_at
Hs.271719.0.A1_3p_at
ILMN_1757132
PH_hs_0025182
TC09000324.hg
Participates
as a component of
SMC5-SMC6 Complex [nucleoplasm] (Homo sapiens)
Inferred To
Smc5 [nucleoplasm]
(Rattus norvegicus)
smc5 [nucleoplasm]
(Dictyostelium discoideum)
smc5 [nucleoplasm]
(Xenopus tropicalis)
SMC5 [nucleoplasm]
(Bos taurus)
SMC5 [nucleoplasm]
(Caenorhabditis elegans)
SMC5 [nucleoplasm]
(Gallus gallus)
SMC5 [nucleoplasm]
(Mus musculus)
SMC5 [nucleoplasm]
(Saccharomyces cerevisiae)
SMC5 [nucleoplasm]
(Schizosaccharomyces pombe)
SMC5 [nucleoplasm]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000361138
,
ENSP00000354957
OpenTargets
ENSG00000198887
HPA
ENSG00000198887-SMC5
PRO
Q8IY18
Pharos - Targets
Q8IY18
GlyGen
Q8IY18
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H668 STN1
1
STN1 [nucleoplasm]
(R-HSA-9668821)
0.527
2
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