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RLBP1 [cytosol]
Stable Identifier
R-HSA-2984237
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Retinaldehyde-binding protein 1, RLBP1_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of the neuronal system (Homo sapiens)
Diseases associated with visual transduction (Homo sapiens)
Retinoid cycle disease events (Homo sapiens)
Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)
11cROL binds to RLBP1 to form RLBP1:11cROL (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RDH10,11 oxidise 11cROL to 11cRAL (Homo sapiens)
RLBP1:11cRAL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RDH5 oxidises 11cROL to 11cRAL (Homo sapiens)
RLBP1:11cRAL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:11cRAL dissociates (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:11cRAL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
The retinoid cycle in cones (daylight vision) (Homo sapiens)
AWAT2 transfers PALM to 11cROL forming 11cRPALM (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:11cRPALM [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
An atROL isomerase isomerises atROL to 11cROL (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:atROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1 binds atROL to form RLBP1:atROL (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
RLBP1:atROL [cytosol] (Homo sapiens)
RLBP1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12271 RLBP1
Gene Names
RLBP1, CRALBP
Chain
initiator methionine:, chain:2-317
Reference Genes
BioGPS Gene:6017 RLBP1
COSMIC (genes):RLBP1 RLBP1
CTD Gene:6017 RLBP1
dbSNP Gene:6017 RLBP1
ENSEMBL:ENSG00000140522 RLBP1
ENSEMBL_homo_sapiens_GENE:ENSG00000140522.12 RLBP1
HGNC:10024 RLBP1
KEGG Gene (Homo sapiens):6017 RLBP1
Monarch:6017 RLBP1
NCBI Gene:6017 RLBP1
OMIM:180090 RLBP1
UCSC:P12271 RLBP1
Reference Transcript
RefSeq:NM_000326.4 RLBP1
RefSeq:XM_011521870.2 RLBP1
Other Identifiers
11726763_at
16813062
206154_PM_at
206154_at
35887_at
3638304
3638305
3638306
3638307
3638309
3638312
3638314
3638315
3638316
3638318
3638319
3638321
3638322
6017
7991246
A_23_P163361
GE57730
GO:0005502
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006629
GO:0006766
GO:0006776
GO:0007601
GO:0008289
GO:0019841
GO:0043226
GO:0044297
GO:0050877
GO:0050896
GO:1902936
HMNXSV003055612
ILMN_1751980
L34219_at
TC15001827.hg
g4506540_3p_at
Participates
as a component of
RLBP1:11cRPALM [cytosol] (Homo sapiens)
RLBP1:atROL [cytosol] (Homo sapiens)
RLBP1:11cROL [cytosol] (Homo sapiens)
RLBP1:11cRAL [cytosol] (Homo sapiens)
as an input of
RLBP1 binds atROL to form RLBP1:atROL (Homo sapiens)
11cROL binds to RLBP1 to form RLBP1:11cROL (Homo sapiens)
as an output of
RLBP1:11cRAL dissociates (Homo sapiens)
Inferred To
CRALBPb [cytosol]
(Danio rerio)
Dmel\CG10657 [cytosol]
(Drosophila melanogaster)
Homologues of RLBP1 [cytosol]
(Drosophila melanogaster)
rlbp1 [cytosol]
(Xenopus tropicalis)
Rlbp1 [cytosol]
(Rattus norvegicus)
Cralbp [cytosol]
(Drosophila melanogaster)
RLBP1 [cytosol]
(Bos taurus)
RLBP1 [cytosol]
(Canis familiaris)
RLBP1 [cytosol]
(Dictyostelium discoideum)
RLBP1 [cytosol]
(Gallus gallus)
RLBP1 [cytosol]
(Mus musculus)
RLBP1 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_000317.1
,
XP_011520172.1
Guide to Pharmacology - Targets
2545
OpenTargets
ENSG00000140522
HPA
ENSG00000140522-RLBP1
GeneCards
P12271
Ensembl
ENSG00000140522
,
ENSP00000268125
,
ENST00000268125
PRO
P12271
Pharos - Targets
P12271
Orphanet
15213
PDB
3HX3
,
4CIZ
,
3HY5
,
4CJ6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9P2G9-2 KLHL8
0.556
3
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