Reactome | NQO2 [cytosol]

NQO2 [cytosol]

Stable Identifier

R-HSA-2980908

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ribosyldihydronicotinamide dehydrogenase [quinone] ecNumber1.10.99.2/ecNumber, NQO2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P16083 NQO2

Gene Names

NQO2, NMOR2

Chain

chain:1-231

Reference Genes

BioGPS Gene:4835 NQO2

COSMIC (genes):NQO2 NQO2

CTD Gene:4835 NQO2

dbSNP Gene:4835 NQO2

ENSEMBL:ENSG00000124588 NQO2

HGNC:7856 NQO2

KEGG:hsa:4835 NQO2

Monarch:4835 NQO2

NCBI Gene:4835 NQO2

OMIM:160998 NQO2

UCSC:P16083 NQO2

Reference Transcript

Other Identifiers

11722053_a_at

17004273

203814_PM_s_at

203814_s_at

2892261

2892263

2892269

2892276

2892278

2892279

2892280

2892281

2892285

2892287

2892289

2892290

2892292

2892294

2892298

2892299

2892300

2892301

2892302

2892305

2892306

2892308

2892312

2892313

2892314

2939184

36880_at

4835

8116610

A_14_P104741

A_21_P0004718

GE60526

GO:0001512

GO:0003824

GO:0003955

GO:0005515

GO:0005654

GO:0005737

GO:0005829

GO:0008270

GO:0009055

GO:0016491

GO:0016661

GO:0031404

GO:0042803

GO:0043226

GO:0046872

GO:0070062

GO:0071949

GO:1901662

GO:1904408

GO:1905594

HMNXSV003044627

ILMN_1712918

J02888_at

PH_hs_0025826

TC06004062.hg

g4505416_3p_s_at

Participates

as a component of

NQO2:FAD [cytosol] (Homo sapiens)

Inferred To

nqo1 [cytosol] (Xenopus tropicalis)

NQO2 [cytosol] (Bos taurus)

NQO2 [cytosol] (Canis familiaris)

NQO2 [cytosol] (Gallus gallus)

NQO2 [cytosol] (Mus musculus)

NQO2 [cytosol] (Rattus norvegicus)

NQO2 [cytosol] (Sus scrofa)

Cross References

OpenTargets

ENSG00000124588

ENSEMBL

ENSP00000369822, ENSG00000124588, ENST00000338130, ENSP00000369795, ENST00000380430, ENSP00000337773, ENST00000380455

ZINC - FDA approved

NQO2_HUMAN

ZINC - Substances

NQO2_HUMAN

ZINC - Biogenic

NQO2_HUMAN

ZINC target

P16083

PRO

P16083

PDB

1ZX1, 1QR2, 3UXH, 3TZB, 4GR9, 4FGL, 5LBU, 3O73, 4U7F, 4FGJ, 3GAM, 2QX8, 5LBT, 4U7H, 4ZVM, 3NHS, 5LBZ, 3OWH, 3OX1, 4ZVL, 2QMY, 4XDH, 3OX3, 2QMZ, 3NHF, 3OVM, 2QX9, 4QOF, 4QOH, 3NHK, 2BZS, 2QR2, 7O4D, 3TEM, 3FW1, 3NHU, 4GQI, 3UXE, 3NHW, 4U7G, 3O2N, 3NHY, 5BUC, 3TE7, 4ZVK, 4FGK, 2QX6, 2QX4, 3NHP, 3OX2, 5LBY, 3OWX, 3NHR, 4XDG, 5LBW, 4ZVN, 4QOE, 3G5M, 2QWX, 4QOJ, 4QOD, 4QOG, 3NHJ, 4QOI, 3NHL, 3NFR, 1SG0, 1XI2

ZINC - Investigational

NQO2_HUMAN

ZINC - Metabolites

NQO2_HUMAN

IntEnz

1.10.5.1

HPA

ENSG00000124588-NQO2

GeneCards

NQO2

Pharos - Targets

P16083

ZINC - Predictions - Purchasable

NQO2_HUMAN

HMDB Protein

HMDBP00138

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IWL3 HSCB	5	HSCB [mitochondrial matrix] (R-HSA-1299438) HSCB(1-30) [mitochondrial matrix] (R-HSA-8986120) HSCB(1-235) [mitochondrial inner membrane] (R-HSA-1299443) HSCB [mitochondrial inner membrane] (R-HSA-1299447) HSCB(1-235) [mitochondrial intermembrane space] (R-HSA-1299456)	0.548	4