Reactome | CXCR3 [plasma membrane]

CXCR3 [plasma membrane]

Stable Identifier

R-HSA-2980699

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

C-X-C chemokine receptor type 3, CXCR3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P49682 CXCR3

Gene Names

CXCR3, GPR9

Chain

chain:1-368

Reference Genes

BioGPS Gene:2833 CXCR3

COSMIC (genes):CXCR3 CXCR3

CTD Gene:2833 CXCR3

dbSNP Gene:2833 CXCR3

ENSEMBL:ENSG00000186810 CXCR3

HGNC:4540 CXCR3

KEGG Gene (Homo sapiens):2833 CXCR3

Monarch:2833 CXCR3

NCBI Gene:2833 CXCR3

OMIM:300574 CXCR3

UCSC:P49682 CXCR3

Reference Transcript

Other Identifiers

0002970066

11734606_a_at

17111955

207681_at

217119_s_at

2833

34077_at

4011990

4011991

4011992

4011993

4011994

4011995

4011996

4011997

4011998

4011999

8173493

A_23_P114299

A_33_P3389230

GE87847

GO:0001525

GO:0001937

GO:0002376

GO:0002685

GO:0003674

GO:0004930

GO:0004950

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005886

GO:0005887

GO:0006810

GO:0006915

GO:0006935

GO:0006950

GO:0006954

GO:0006955

GO:0007155

GO:0007165

GO:0007166

GO:0007186

GO:0007189

GO:0007204

GO:0008150

GO:0008219

GO:0008283

GO:0008284

GO:0009058

GO:0009897

GO:0009986

GO:0010818

GO:0016020

GO:0016021

GO:0016493

GO:0016494

GO:0016525

GO:0019722

GO:0019956

GO:0019957

GO:0019958

GO:0030155

GO:0034641

GO:0038023

GO:0040011

GO:0042592

GO:0045766

GO:0045944

GO:0048646

GO:0048856

GO:0048870

GO:0050921

GO:0051281

GO:0055085

GO:0060326

GO:0070098

GO:0071954

GO:1900118

GO:1900119

HMNXSV003005786

Hs.198252.1.S1_3p_a_at

ILMN_1797975

PH_hs_0027971

TC0X001128.hg

U32674_s_at

X95876_at

g4504098_3p_at

Participates

as an input of

Receptor CXCR3 binds ligands CXCL9 to 11 (Homo sapiens)

as a component of

CXCR3:CXCR3 ligands [plasma membrane] (Homo sapiens)

Inferred To

CXCR3 [plasma membrane] (Bos taurus)

CXCR3 [plasma membrane] (Sus scrofa)

cxcr3.1 [plasma membrane] (Danio rerio)

Cxcr3 [plasma membrane] (Mus musculus)

Cxcr3 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001495.1, NP_001136269.1, XP_016884924.1

Guide to Pharmacology - Targets

OpenTargets

ENSG00000186810

ZINC - Substances

CXCR3_HUMAN

GeneCards

P49682

HPA

ENSG00000186810-CXCR3

Ensembl

ENSG00000186810, ENSP00000362797, ENST00000373693, ENSP00000362795, ENST00000373691

ZINC target

P49682

PRO

P49682

Pharos - Targets

P49682

ZINC - Predictions - Purchasable

CXCR3_HUMAN

GlyGen

P49682

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14523 C2C2L			0.556	3
UniProt:Q9Y6G1 TM14A			0.556	3
UniProt:Q8N6F1-2 CLDN19			0.556	3
UniProt:P61073 CXCR4	1	CXCR4 [plasma membrane] (R-HSA-2980772)	0.512	5
UniProt:P49682 CXCR3	1	CXCR3 [plasma membrane] (R-HSA-2980699)	0.463	3

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