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ABR [cytosol]
Stable Identifier
R-HSA-2975963
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Active breakpoint cluster region-related protein, ABR_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 GAPs stimulate RAC2 GTPase activity (Homo sapiens)
RAC2 GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RAC2 GEFs activate RAC2 (Homo sapiens)
RAC2 GEFs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GAPs stimulate RAC3 GTPase activity (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GAPs stimulate RHOA GTPase activity (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
ABR [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12979 ABR
Gene Names
ABR
Chain
chain:1-859
Reference Genes
BioGPS Gene:29 ABR
COSMIC (genes):ABR ABR
CTD Gene:29 ABR
dbSNP Gene:29 ABR
ENSEMBL:ENSG00000159842 ABR
HGNC:81 ABR
KEGG:hsa:29 ABR
Monarch:29 ABR
NCBI Gene:29 ABR
OMIM:600365 ABR
UCSC:Q12979 ABR
Reference Transcript
RefSeq:NM_001282149.1 ABR
RefSeq:NM_021962.4 ABR
RefSeq:NM_001159746.2 ABR
RefSeq:NM_001322840.1 ABR
RefSeq:NM_001092.4 ABR
RefSeq:NM_001256847.2 ABR
Other Identifiers
11716686_a_at
11716687_x_at
11741077_x_at
11758096_s_at
16839294
212895_PM_s_at
212895_s_at
214671_PM_s_at
214671_s_at
231400_PM_s_at
231400_s_at
29
3739961
3739963
3739964
3739965
3739966
3739967
3739968
3739969
3739970
3739971
3739972
3739973
3739974
3739975
3739976
3739977
3739978
3739979
3739993
3739994
3740001
3740002
3740003
3740004
3740005
3740006
3740007
3740008
3740009
3740010
3740011
3740012
3740013
3740014
3740015
3740022
3740023
3740024
3740025
3740026
3740028
3740029
3740033
3740041
3740042
3740045
3740046
3740047
3740048
3740052
3740072
3740074
3740075
3740076
3740077
3740078
3740089
39058_at
4041037
4041038
4041039
4041040
4041042
4041043
4041044
4041046
4041048
4041050
4041052
4041054
58660_s_at
8010983
A_23_P503182
A_33_P3372297
GE58847
GO:0003824
GO:0004674
GO:0005085
GO:0005096
GO:0005515
GO:0005829
GO:0006468
GO:0007165
GO:0007264
GO:0016020
GO:0016740
GO:0030424
GO:0035556
GO:0042995
GO:0043197
GO:0043547
GO:0045202
GO:0050804
GO:0051056
GO:0090630
GO:0098685
GO:0098772
GO:0098978
GO:0140096
HMNXSV003025542
HMNXSV003026517
Hs.118021.2.A1_3p_a_at
Hs.118021.3.A1_3p_a_at
Hs.87595.2.A1_3p_at
ILMN_1655114
ILMN_1657045
ILMN_1672878
PH_hs_0025302
TC17000970.hg
U01147_at
p33680
Participates
as a candidate of
RHOA GAPs [cytosol] (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
RAC2 GAPs [cytosol] (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
as a member of
RAC2 GEFs [cytosol] (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
RhoGAP1A [cytosol]
(Drosophila melanogaster)
Abr [cytosol]
(Mus musculus)
Abr [cytosol]
(Rattus norvegicus)
ABR [cytosol]
(Bos taurus)
ABR [cytosol]
(Canis familiaris)
ABR [cytosol]
(Gallus gallus)
ABR [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001153218.1
,
NP_068781.2
,
NP_001083.2
,
NP_001309769.1
,
NP_001269078.1
,
NP_001243776.1
OpenTargets
ENSG00000159842
ENSEMBL
ENST00000291107
,
ENSP00000303909
,
ENSP00000442048
,
ENST00000302538
,
ENST00000611021
,
ENST00000627258
,
ENST00000625740
,
ENST00000544583
,
ENST00000543210
,
ENSP00000478880
,
ENST00000612118
,
ENSP00000481740
,
ENSP00000479455
,
ENSP00000291107
,
ENSP00000483168
,
ENSP00000445198
,
ENST00000615642
,
ENST00000620619
,
ENSP00000484030
,
ENSP00000486214
,
ENST00000611009
,
ENSP00000486511
HPA
ENSG00000159842-ABR
PRO
Q12979
Pharos - Targets
Q12979
HMDB Protein
HMDBP08298
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