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ABCG1 [plasma membrane]
Stable Identifier
R-HSA-2975951
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ATP-binding cassette sub-family G member 1, ABCG1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
NR1H2 and NR1H3-mediated signaling (Homo sapiens)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Homo sapiens)
Expression of ABCG1 regulated by NR1H2,3 (Homo sapiens)
ABCG1 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
ABC transporters in lipid homeostasis (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ABCG1 dimer [plasma membrane] (Homo sapiens)
ABCG1 [plasma membrane] (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein remodeling (Homo sapiens)
HDL remodeling (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ABCG1 dimer [plasma membrane] (Homo sapiens)
ABCG1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P45844 ABCG1
Gene Names
ABCG1, ABC8, WHT1
Chain
chain:1-678
Reference Genes
BioGPS Gene:9619 ABCG1
COSMIC (genes):ABCG1 ABCG1
CTD Gene:9619 ABCG1
dbSNP Gene:9619 ABCG1
ENSEMBL:ENSG00000160179 ABCG1
HGNC:73 ABCG1
KEGG:hsa:9619 ABCG1
Monarch:9619 ABCG1
NCBI Gene:9619 ABCG1
OMIM:603076 ABCG1
UCSC:P45844 ABCG1
Reference Transcript
RefSeq:NM_016818.2 ABCG1
RefSeq:NM_207174.1 ABCG1
RefSeq:NM_207627.1 ABCG1
RefSeq:NM_004915.3 ABCG1
RefSeq:NM_207628.1 ABCG1
RefSeq:NM_207629.1 ABCG1
Other Identifiers
11725515_a_at
11725516_s_at
11725517_x_at
11726492_a_at
11750659_a_at
16923145
204567_PM_s_at
204567_s_at
211113_PM_s_at
211113_s_at
230913_PM_at
230913_at
232081_PM_at
232081_at
3922445
3922448
3922449
3922453
3922454
3922455
3922457
3922458
3922460
3922461
3922469
3922470
3922489
3922490
3922491
3922492
3922493
3922494
3922504
3922505
3922506
3922507
3922514
3922515
3922516
3922517
3922518
3922519
3922520
3922521
3922522
3922523
3922524
3922528
3922529
3922530
3922531
3922532
3922533
3922534
3922535
3922536
3922537
3922538
3922539
3922540
3922541
3922542
3922543
3922548
3922550
41362_at
47346_at
60924_i_at
60925_r_at
8068761
9619
A_23_P166297
A_32_P147063
A_32_P203749
GE60140
GE85438
GE87127
GO:0000139
GO:0003824
GO:0005215
GO:0005515
GO:0005524
GO:0005543
GO:0005739
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006629
GO:0006869
GO:0008203
GO:0008289
GO:0009897
GO:0010745
GO:0010875
GO:0010887
GO:0010888
GO:0015485
GO:0016020
GO:0016787
GO:0016887
GO:0019534
GO:0030301
GO:0031410
GO:0032367
GO:0033344
GO:0033700
GO:0033993
GO:0034041
GO:0034204
GO:0034374
GO:0034375
GO:0034436
GO:0042632
GO:0042803
GO:0042987
GO:0043226
GO:0043531
GO:0043691
GO:0045542
GO:0046982
GO:0046983
GO:0050714
GO:0055037
GO:0055085
GO:0055091
GO:0061024
GO:0071403
GO:0090181
GO:0090554
GO:0120020
GO:0140328
GO:0140359
GO:0140657
GO:1902004
HMNXSV003033325
Hs.59525.0.A1_3p_at
Hs.6655.0.S1_3p_at
ILMN_1658036
ILMN_1658176
ILMN_1695968
ILMN_1743638
ILMN_1794782
ILMN_2262362
ILMN_2329927
PH_hs_0000668
PH_hs_0019668
PH_hs_0024091
TC21000198.hg
TC21000200.hg
TC21000747.hg
TC21000748.hg
X91249_at
g1314276_3p_a_at
g8051574_3p_a_at
p26171
Participates
as an output of
Expression of ABCG1 regulated by NR1H2,3 (Homo sapiens)
as a component of
ABCG1 dimer [plasma membrane] (Homo sapiens)
Inferred To
Dmel\CG3164 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4822 [plasma membrane]
(Drosophila melanogaster)
Homologues of ABCG1 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG9664 [plasma membrane]
(Drosophila melanogaster)
CG7346 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG9663 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG5853 [plasma membrane]
(Drosophila melanogaster)
Atet [plasma membrane]
(Drosophila melanogaster)
Abcg1 [plasma membrane]
(Rattus norvegicus)
ABCG1 [plasma membrane]
(Bos taurus)
ABCG1 [plasma membrane]
(Canis familiaris)
ABCG1 [plasma membrane]
(Dictyostelium discoideum)
ABCG1 [plasma membrane]
(Drosophila melanogaster)
ABCG1 [plasma membrane]
(Gallus gallus)
ABCG1 [plasma membrane]
(Mus musculus)
ABCG1 [plasma membrane]
(Saccharomyces cerevisiae)
ABCG1 [plasma membrane]
(Sus scrofa)
Dmel\CG31689 [plasma membrane]
(Drosophila melanogaster)
abcg1 [plasma membrane]
(Danio rerio)
abcg1 [plasma membrane]
(Xenopus tropicalis)
Cross References
Guide to Pharmacology - Targets
791
ENSEMBL
ENSP00000291524
,
ENSP00000339744
,
ENSP00000381475
,
ENST00000343687
,
ENST00000361802
,
ENST00000347800
,
ENST00000398449
,
ENSP00000354995
,
ENST00000398457
,
ENSP00000381467
OpenTargets
ENSG00000160179
HPA
ENSG00000160179-ABCG1
PRO
P45844
Pharos - Targets
P45844
GlyGen
P45844
PDB
7OZ1
,
7R8C
,
7R8D
,
7FDV
,
7R8E
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