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ABCG1 [plasma membrane]
Stable Identifier
R-HSA-2975951
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ATP-binding cassette sub-family G member 1, ABCG1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
NR1H2 and NR1H3-mediated signaling (Homo sapiens)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Homo sapiens)
Expression of ABCG1 regulated by NR1H2,3 (Homo sapiens)
ABCG1 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
ABC transporters in lipid homeostasis (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ABCG1 dimer [plasma membrane] (Homo sapiens)
ABCG1 [plasma membrane] (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein remodeling (Homo sapiens)
HDL remodeling (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ABCG1 dimer [plasma membrane] (Homo sapiens)
ABCG1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P45844 ABCG1
Gene Names
ABCG1, ABC8, WHT1
Chain
chain:1-678
Reference Genes
BioGPS Gene:9619 ABCG1
COSMIC (genes):ABCG1 ABCG1
CTD Gene:9619 ABCG1
dbSNP Gene:9619 ABCG1
ENSEMBL:ENSG00000160179 ABCG1
ENSEMBL:ENSG00000160179.19 ABCG1
HGNC:73 ABCG1
KEGG Gene (Homo sapiens):9619 ABCG1
Monarch:9619 ABCG1
NCBI Gene:9619 ABCG1
OMIM:603076 ABCG1
UCSC:P45844 ABCG1
Reference Transcript
RefSeq:NM_207629.1 ABCG1
RefSeq:NM_207627.1 ABCG1
RefSeq:NM_207628.1 ABCG1
RefSeq:NM_207174.1 ABCG1
RefSeq:NM_004915.3 ABCG1
RefSeq:NM_016818.2 ABCG1
Other Identifiers
11725515_a_at
11725516_s_at
11725517_x_at
11726492_a_at
11750659_a_at
16923145
204567_PM_s_at
204567_s_at
211113_PM_s_at
211113_s_at
3922445
3922448
3922449
3922454
3922455
3922457
3922458
3922460
3922461
3922469
3922470
3922504
3922505
3922507
3922514
3922515
3922516
3922518
3922520
3922521
3922522
3922523
3922524
3922528
3922531
3922532
3922533
3922534
41362_at
8068761
9619
A_23_P166297
GE60140
GO:0000139
GO:0000166
GO:0003824
GO:0005215
GO:0005515
GO:0005524
GO:0005543
GO:0005739
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006629
GO:0006869
GO:0008203
GO:0008289
GO:0009897
GO:0010033
GO:0010745
GO:0010875
GO:0010887
GO:0010888
GO:0015485
GO:0016020
GO:0016787
GO:0016887
GO:0019534
GO:0030154
GO:0030301
GO:0031410
GO:0032367
GO:0033344
GO:0033700
GO:0033993
GO:0034041
GO:0034204
GO:0034374
GO:0034375
GO:0034436
GO:0042632
GO:0042803
GO:0042987
GO:0043226
GO:0043531
GO:0043691
GO:0045542
GO:0046982
GO:0046983
GO:0050714
GO:0055037
GO:0055085
GO:0055091
GO:0061024
GO:0071403
GO:0090181
GO:0090554
GO:0120009
GO:0120020
GO:0140328
GO:0140359
GO:0140657
GO:1901998
GO:1902004
HMNXSV003033325
ILMN_1658176
ILMN_1695968
ILMN_1794782
ILMN_2262362
ILMN_2329927
PH_hs_0024091
TC21000198.hg
X91249_at
g1314276_3p_a_at
g8051574_3p_a_at
Participates
as an output of
Expression of ABCG1 regulated by NR1H2,3 (Homo sapiens)
as a component of
ABCG1 dimer [plasma membrane] (Homo sapiens)
Inferred To
Dmel\CG3164 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4822 [plasma membrane]
(Drosophila melanogaster)
Homologues of ABCG1 [plasma membrane]
(Dictyostelium discoideum)
Homologues of ABCG1 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG9664 [plasma membrane]
(Drosophila melanogaster)
CG7346 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG9663 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG5853 [plasma membrane]
(Drosophila melanogaster)
Atet [plasma membrane]
(Drosophila melanogaster)
Abcg1 [plasma membrane]
(Rattus norvegicus)
ABCG1 [plasma membrane]
(Bos taurus)
ABCG1 [plasma membrane]
(Canis familiaris)
ABCG1 [plasma membrane]
(Danio rerio)
ABCG1 [plasma membrane]
(Dictyostelium discoideum)
ABCG1 [plasma membrane]
(Drosophila melanogaster)
ABCG1 [plasma membrane]
(Gallus gallus)
ABCG1 [plasma membrane]
(Mus musculus)
ABCG1 [plasma membrane]
(Plasmodium falciparum)
ABCG1 [plasma membrane]
(Sus scrofa)
Dmel\CG31689 [plasma membrane]
(Drosophila melanogaster)
abcg1 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_997511.1
,
NP_997512.1
,
NP_004906.3
,
NP_997510.1
,
NP_058198.2
,
NP_997057.1
Guide to Pharmacology - Targets
791
OpenTargets
ENSG00000160179
HPA
ENSG00000160179-ABCG1
GeneCards
P45844
Ensembl
ENSP00000339744
,
ENSG00000160179
,
ENST00000343687
,
ENSP00000291524
,
ENST00000398449
,
ENSP00000381467
,
ENST00000347800
,
ENST00000361802
,
ENSP00000381475
,
ENST00000398457
,
ENSP00000354995
PRO
P45844
Pharos - Targets
P45844
Orphanet
27923
PDB
7R8D
,
7OZ1
,
7FDV
,
7R8C
,
7R8E
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