POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter

Stable Identifier
R-HSA-2972964
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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POU5F1 (OCT4), SOX2, NANOG bind the FOXD3 promoter
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The FOXD3 gene is bound by POU5F1 (OCT4) (Boyer et al. 2005, Jung et al. 2010), SOX2 (Boyer et al. 2005, Lister et al. 2009), and NANOG (Boyer et al. 2005, Lister et al. 2009) and POU5F1 activates expression (Babaie et al. 2007, Kunarso et al. 2010).

Literature References
PubMed ID Title Journal Year
19829295 Human DNA methylomes at base resolution show widespread epigenomic differences

Thomson, JA, Nery, JR, Ye, Z, Pelizzola, M, Ruotti, V, Lister, R, Antosiewicz-Bourget, J, Tonti-Filippini, J, Edsall, L, Hawkins, RD, Lee, L, Ecker, JR, Dowen, RH, Hon, G, Ren, B, Ngo, QM, Stewart, R, Millar, AH

Nature 2009
20526341 Transposable elements have rewired the core regulatory network of human embryonic stem cells

Ng, HH, Chan, YS, Bourque, G, Chia, NY, Hwang, C, Kunarso, G, Lu, X, Jeyakani, J

Nat. Genet. 2010
16153702 Core transcriptional regulatory circuitry in human embryonic stem cells

Gifford, DK, Jaenisch, R, Lee, TI, Young, RA, Kumar, RM, Guenther, MG, Levine, SS, Boyer, LA, Jenner, RG, Cole, MF, Zucker, JP, Murray, HL, Johnstone, SE, Melton, DA

Cell 2005
17068183 Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

Babaie, Y, Groth, D, Wruck, W, Greber, B, Lehrach, H, Brink, TC, Burdon, T, Herwig, R, Adjaye, J

Stem Cells 2007
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Authored
May, B  (2013-01-03)
Reviewed
Wang, J  (2014-01-23)
Created
D'Eustachio, P  (2013-01-06)
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