Reactome | EXOC7 [plasma membrane]

EXOC7 [plasma membrane]

Stable Identifier

R-HSA-2872288

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UPT5 EXOC7

Gene Names

EXOC7, EXO70, KIAA1067

Chain

chain:1-735

Reference Genes

BioGPS Gene:23265 EXOC7

COSMIC (genes):EXOC7 EXOC7

CTD Gene:23265 EXOC7

dbSNP Gene:23265 EXOC7

ENSEMBL:ENSG00000182473 EXOC7

ENSEMBL:ENSG00000182473.22 EXOC7

HGNC:23214 EXOC7

KEGG Gene (Homo sapiens):23265 EXOC7

Monarch:23265 EXOC7

NCBI Gene:23265 EXOC7

OMIM:608163 EXOC7

UCSC:Q9UPT5 EXOC7

Reference Transcript

Other Identifiers

11719770_a_at

11719771_a_at

11755489_a_at

11755490_x_at

11756454_a_at

16849098

212026_PM_s_at

212026_s_at

212034_PM_s_at

212034_s_at

212035_PM_s_at

212035_s_at

215413_PM_at

215413_at

23265

3771337

3771338

3771339

3771340

3771341

3771342

3771343

3771344

3771345

3771346

3771348

3771350

3771351

3771352

3771354

3771356

3771358

3771359

3771360

3771361

3771363

3771364

3771366

3771370

3771372

3771373

3771375

3771377

3771378

3771379

3771381

3771383

3771384

8018620

A_23_P100556

A_23_P89159

A_23_P89163

A_33_P3390032

GE904875

GO:0000145

GO:0000278

GO:0000281

GO:0000910

GO:0005515

GO:0005546

GO:0005737

GO:0005815

GO:0005829

GO:0005856

GO:0005886

GO:0006887

GO:0006904

GO:0006914

GO:0008289

GO:0015031

GO:0016020

GO:0016192

GO:0016241

GO:0032584

GO:0034451

GO:0043226

GO:0061024

GO:0090148

GO:0090522

GO:0090543

GO:2000535

HMNXSV003002448

HMNXSV003010121

HMNXSV003027547

Hs.325530.0.A1_3p_a_at

Hs.325530.0.A2_3p_a_at

Hs.325530.0.A3_3p_a_at

Hs.325530.1.A1_3p_a_at

ILMN_1750011

ILMN_1815012

PH_hs_0026682

TC17001893.hg

TC17002788.hg

Participates

as a component of

Exocyst Complex [plasma membrane] (Homo sapiens)

as an input of

Exocyst complex formation (Homo sapiens)

Other forms of this molecule

EXOC7 [cytosol]

Inferred To

exoc-7 [plasma membrane] (Caenorhabditis elegans)

exoc7 [plasma membrane] (Danio rerio)

exoc7 [plasma membrane] (Dictyostelium discoideum)

exoc7 [plasma membrane] (Xenopus tropicalis)

exo70 [plasma membrane] (Schizosaccharomyces pombe)

Exoc7 [plasma membrane] (Mus musculus)

Exoc7 [plasma membrane] (Rattus norvegicus)

EXOC7 [plasma membrane] (Bos taurus)

EXOC7 [plasma membrane] (Canis familiaris)

EXOC7 [plasma membrane] (Gallus gallus)

EXOC7 [plasma membrane] (Sus scrofa)

Exo70 [plasma membrane] (Drosophila melanogaster)

EXO70 [plasma membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_056034.2, NP_001138771.1, NP_001138769.1, NP_001269242.1, NP_001013861.1, NP_001138770.1

OpenTargets

ENSG00000182473

HPA

ENSG00000182473-EXOC7

GeneCards

Q9UPT5

Ensembl

ENST00000634349, ENSP00000489266, ENST00000589210, ENST00000335146, ENSP00000468404, ENSP00000404322, ENST00000332065, ENSP00000334100, ENSP00000333806, ENSG00000182473, ENST00000411744

PRO

Q9UPT5

Pharos - Targets

Q9UPT5

HMDB Protein

HMDBP08386

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.666	4
UniProt:Q8IY31 IFT20	3	IFT20 [cilium] (R-HSA-5617624) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [ciliary tip] (R-HSA-5625355)	0.666	4
UniProt:Q96A65 EXOC4	2	EXOC4 [plasma membrane] (R-HSA-264989) EXOC4 [cytosol] (R-HSA-5623381)	0.638	4
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.556	5
UniProt:A1L4H1 SSC5D	1	SSC5D [extracellular region] (R-HSA-8878615)	0.556	3
UniProt:Q99459 CDC5L	1	CDC5L [nucleoplasm] (R-HSA-5420887)	0.547	2
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.508	2
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-265045) EXOC5 [cytosol] (R-HSA-5623383)	0.508	3
UniProt:Q8TAG9 EXOC6	2	EXOC6 [plasma membrane] (R-HSA-265041) EXOC6 [cytosol] (R-HSA-5623384)	0.508	3
UniProt:Q9Y2D4 EXC6B			0.508	4
UniProt:O60645 EXOC3	2	EXOC3 [cytosol] (R-HSA-5623379) EXOC3 [secretory granule membrane] (R-HSA-2872286)	0.508	2
UniProt:Q9NV70 EXOC1	2	EXOC1 [plasma membrane] (R-HSA-2872284) EXOC1 [cytosol] (R-HSA-5623375)	0.508	2
UniProt:Q9WMX2 POLG			0.499	3
UniProt:Q9BXC9 BBS2	1	BBS2 [cytosol] (R-HSA-5617637)	0.463	2
UniProt:Q86VI4 LAP4B			0.463	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.463	2

Cite Us!