NOTCH1 PEST domain mutants bind JAG1

Stable Identifier
R-HSA-2768999
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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NOTCH1 PEST domain mutants are expected to bind to JAG1 ligand in an identical fashion to wild-type NOTCH1 (Li et al. 1998, Benedito et al. 2009).

Literature References
PubMed ID Title Journal Year
19524514 The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

Benedito, R, Roca, C, Sörensen, I, Adams, S, Gossler, A, Fruttiger, M, Adams, RH

Cell 2009
9462510 The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1

Li, L, Milner, LA, Deng, Y, Iwata, M, Banta, AB, Graf, L, Marcovina, S, Friedman, C, Trask, BJ, Hood, L, Torok-Storb, B

Immunity 1998
Participants
Participant Of
Normal reaction
Disease
Name Identifier Synonyms
T-cell leukemia 715
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created
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