Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
FXYD1 [plasma membrane]
Stable Identifier
R-HSA-2752086
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Phospholemman, PLM_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
Potential therapeutics for SARS (Homo sapiens)
ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Ion transport by P-type ATPases (Homo sapiens)
ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
FXYDs [plasma membrane] (Homo sapiens)
FXYD1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00168 FXYD1
Gene Names
FXYD1, PLM
Chain
signal peptide:1-20, chain:21-92
Reference Genes
BioGPS Gene:5348 FXYD1
COSMIC (genes):FXYD1 FXYD1
CTD Gene:5348 FXYD1
dbSNP Gene:5348 FXYD1
ENSEMBL:ENSG00000266964 FXYD1
ENSEMBL_homo_sapiens_GENE:ENSG00000266964.6 FXYD1
HGNC:4025 FXYD1
KEGG Gene (Homo sapiens):5348 FXYD1
Monarch:5348 FXYD1
NCBI Gene:5348 FXYD1
OMIM:602359 FXYD1
UCSC:O00168 FXYD1
Reference Transcript
RefSeq:XM_017026874.1 FXYD1
RefSeq:NM_001278718.1 FXYD1
RefSeq:NM_005031.4 FXYD1
RefSeq:NM_021902.3 FXYD1
RefSeq:NM_001278717.1 FXYD1
Other Identifiers
11723552_a_at
11753824_x_at
16860902
205384_PM_at
205384_at
32109_at
3830190
3830191
3830192
3830193
3830194
3830195
3830197
3830200
3830201
3830202
3830203
3830204
3830206
3830207
5348
8027760
A_14_P106642
A_23_P108216
A_33_P3228435
GE59379
GO:0003012
GO:0003013
GO:0005215
GO:0005254
GO:0005886
GO:0005890
GO:0005901
GO:0006811
GO:0006813
GO:0006814
GO:0006821
GO:0006936
GO:0008016
GO:0010734
GO:0014704
GO:0016020
GO:0016324
GO:0017080
GO:0030315
GO:0036211
GO:0042383
GO:0043269
GO:0044325
GO:0055085
GO:0086036
GO:0098772
GO:0099106
GO:1902476
GO:1903278
GO:2000649
HMNXSV003028673
HMNXSV003030149
ILMN_1764022
ILMN_1789463
ILMN_2345292
TC19000459.hg
g11612671_3p_at
Participates
as a member of
FXYDs [plasma membrane] (Homo sapiens)
Inferred To
FXYD1 [plasma membrane]
(Bos taurus)
FXYD1 [plasma membrane]
(Canis familiaris)
FXYD1 [plasma membrane]
(Gallus gallus)
FXYD1 [plasma membrane]
(Sus scrofa)
Fxyd1 [plasma membrane]
(Mus musculus)
Fxyd1 [plasma membrane]
(Rattus norvegicus)
fxyd1 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_068702.1
,
NP_001265646.1
,
NP_001265647.1
,
XP_016882363.1
,
NP_005022.2
Guide to Pharmacology - Targets
3152
OpenTargets
ENSG00000266964
GeneCards
O00168
HPA
ENSG00000266964-FXYD1
Ensembl
ENSP00000468535
,
ENST00000351325
,
ENSP00000343314
,
ENSP00000467727
,
ENST00000612146
,
ENST00000589209
,
ENST00000588715
,
ENSP00000393611
,
ENSG00000266964
,
ENST00000588081
,
ENSP00000481244
,
ENST00000588607
,
ENST00000455515
,
ENSP00000465289
,
ENSP00000466398
PRO
O00168
Pharos - Targets
O00168
PDB
2JO1
HMDB Protein
HMDBP08159
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92597 NDRG1
1
NDRG1 [cytosol]
(R-HSA-5628834)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text