Reactome | FXYD3 [plasma membrane]

FXYD3 [plasma membrane]

Stable Identifier

R-HSA-2752084

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

FXYD domain-containing ion transport regulator 3, FXYD3_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - Potential therapeutics for SARS (Homo sapiens)
        
        ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)
        
        ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
        
        FXYDs [plasma membrane] (Homo sapiens)
        
        FXYD3 [plasma membrane] (Homo sapiens)
        
        ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
        
        ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
        
        FXYDs [plasma membrane] (Homo sapiens)
        
        FXYD3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14802 FXYD3

Gene Names

FXYD3, MAT8, PLML

Chain

signal peptide:1-20, chain:21-87

Reference Genes

BioGPS Gene:5349 FXYD3

COSMIC (genes):FXYD3 FXYD3

CTD Gene:5349 FXYD3

dbSNP Gene:5349 FXYD3

ENSEMBL:ENSG00000089356 FXYD3

ENSEMBL_homo_sapiens_GENE:ENSG00000089356.19 FXYD3

HGNC:4027 FXYD3

KEGG Gene (Homo sapiens):5349 FXYD3

Monarch:5349 FXYD3

NCBI Gene:5349 FXYD3

OMIM:604996 FXYD3

UCSC:Q14802 FXYD3

Reference Transcript

Other Identifiers

11733254_a_at

11734193_a_at

11741254_a_at

11741788_at

11754040_a_at

11754041_x_at

16860888

202488_PM_s_at

202488_s_at

202489_PM_s_at

202489_s_at

3830167

3830168

3830169

3830170

3830171

3830172

3830175

3830176

3830177

3830179

3830181

3830182

3830183

3830184

3830185

3830186

3830187

3830188

39087_at

5349

8027748

A_24_P293192

A_33_P3228450

A_33_P3228455

A_33_P3228460

A_33_P3228466

GE80330

GE87022

GO:0005215

GO:0005254

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0005789

GO:0005886

GO:0006811

GO:0006813

GO:0006814

GO:0006821

GO:0016020

GO:0017080

GO:0043226

GO:0043269

GO:0051117

GO:0055085

GO:0070062

GO:0098772

GO:0099106

GO:1902476

HMNXSV003033936

HMNXSV003057750

ILMN_1665372

ILMN_1791580

PH_hs_0015534

TC19000458.hg

U28249_at

X93036_at

g11612675_3p_a_at

g13528881_3p_a_at

Participates

as a member of

FXYDs [plasma membrane] (Homo sapiens)

Inferred To

fxyd1 [plasma membrane] (Xenopus tropicalis)

Fxyd3 [plasma membrane] (Mus musculus)

Fxyd3 [plasma membrane] (Rattus norvegicus)

FXYD3 [plasma membrane] (Bos taurus)

FXYD3 [plasma membrane] (Canis familiaris)

FXYD3 [plasma membrane] (Gallus gallus)

Cross References

RefSeq

NP_001129479.1, NP_001129484.1, NP_001129483.1, XP_016882367.1, NP_001129482.1, NP_068710.1, XP_016882366.1, NP_001129481.1, NP_001129480.1, NP_005962.1, XP_005259053.1

Guide to Pharmacology - Targets

3153

OpenTargets

ENSG00000089356

GeneCards

Q14802

HPA

ENSG00000089356-FXYD3

Ensembl

ENSP00000474851, ENSP00000474855, ENST00000605552, ENST00000344013, ENSP00000474055, ENSP00000474526, ENSP00000474438, ENSP00000328259, ENST00000603181, ENSP00000339499, ENST00000604255, ENSG00000089356, ENST00000435734, ENSP00000389770, ENSP00000473929, ENST00000604404, ENST00000604621, ENST00000603449, ENST00000346446, ENSP00000474622, ENST00000605677

PRO

Q14802

Pharos - Targets

Q14802

HMDB Protein

HMDBP08197

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43889 CREB3	7	CREB3(1-256) [nucleoplasm] (R-HSA-8874190) CREB3(1-256) [cytosol] (R-HSA-8874135) CREB3(1-291) [Golgi membrane] (R-HSA-8874181) CREB3(257-291) [Golgi membrane] (R-HSA-8874207) CREB3 [Golgi membrane] (R-HSA-8874123) CREB3(292-371) [Golgi membrane] (R-HSA-8874173) CREB3 [endoplasmic reticulum membrane] (R-HSA-8874165)	0.553	2