Phosphorylation of PLC-gamma

Stable Identifier
R-HSA-2730888
Type
Reaction
Species
Homo sapiens
Compartment
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Tyrosine phosphorylation of PLC-gamma enhances its catalytic activity. BTK and SYK are involved in the phosphorylation of PLC-gamma (PLCG). Phosphorylation of tyrosine residues 753, 759, 1197, and 1217 in PLCG2 and 771, 783, and 1254 in PLCG1 have been identified as BTK/SYK-dependent phosphorylation sites.

Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of p-SYK/p-BTK [plasma membrane]

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